Effects of Low-Dose Doxycycline on Oral Bone Loss

PHASE3CompletedINTERVENTIONAL
Enrollment

128

Participants

Timeline

Start Date

June 1, 2002

Primary Completion Date

October 1, 2005

Study Completion Date

October 1, 2005

Conditions
Periodontitis
Interventions
DRUG

20 mg doxycycline hyclate

Subjects in the LDD group took 20 mg doxycycline hyclate tablets twice daily for two years

DRUG

Placebo

Subjects in the placebo group took a placebo look-alike twice daily for two years.

Trial Locations (2)

68583-0740

University of Nebraska Medical Center, College of Dentistry, Lincoln

11794-8702

Department of Oral Biology and Pathology, Stony Brook

All Listed Sponsors
collaborator

National Institute of Dental and Craniofacial Research (NIDCR)

NIH

lead

University of Nebraska

OTHER

NCT00066027 - Effects of Low-Dose Doxycycline on Oral Bone Loss | Biotech Hunter | Biotech Hunter