23
Participants
Start Date
July 31, 2003
Primary Completion Date
December 31, 2010
Study Completion Date
December 31, 2010
Simvastatin Susp.
During the simvastatin phase of the trial, therapy will be initiated at 0.5 mg/kg/day for six weeks and then increased to 1.0 mg/kg/day if adverse side effects are minimal or absent.
OraPlus
During this trial and for two months prior, patients will be maintained on 150 mg/kg/day of dietary cholesterol (150 mg/ml in OraPlus) for the duration of the trial
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Forbes Porter, M.D.
NIH