Safety of an HIV Vaccine (AVX101) in HIV Uninfected Volunteers in the United States and South Africa

PHASE1CompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

July 31, 2003

Primary Completion Date

July 31, 2005

Study Completion Date

July 31, 2005

Conditions
HIV Infections
Interventions
BIOLOGICAL

AVX101

Alphavirus replicon particle vaccine expressing HIV Gag antigen

OTHER

placebo

phosphate buffered saline, pH 7.2, HSA, sodium gluconate, and sucrose

Trial Locations (7)

10032

Columbia University, New York

10456

New York Blood Ctr- Union Square, The Bronx

37232

Vanderbilt University, Nashville

21205-1901

Johns Hopkins University, Baltimore

14642-0002

University of Rochester Medical Center, Rochester

Unknown

SAAVI Vaccine Research Unit, Durban

Chris Hani Baragwanath Hospital, Soweto

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

HIV Vaccine Trials Network

NETWORK

collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

AlphaVax, Inc.

INDUSTRY