NCT00060424 - Fludarabine Phosphate and Total-Body Irradiation Before Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

March 31, 2003

Primary Completion Date

September 30, 2010

Study Completion Date

September 22, 2010

Conditions

B-Cell Prolymphocytic LeukemiaChronic Lymphocytic LeukemiaProlymphocytic LeukemiaRecurrent Chronic Lymphocytic LeukemiaRecurrent Small Lymphocytic LymphomaRefractory Chronic Lymphocytic LeukemiaT-Cell Prolymphocytic Leukemia

Interventions

DRUG

Cyclosporine

Given PO

DRUG

Fludarabine Phosphate

Given IV

PROCEDURE

Hematopoietic Cell Transplantation

Undergo allogeneic peripheral blood stem cell transplant

OTHER

Laboratory Biomarker Analysis

Correlative studies

DRUG

Mycophenolate Mofetil

Given PO

PROCEDURE

Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation

Undergo allogeneic peripheral blood stem cell transplant

RADIATION

Total-Body Irradiation

Undergo TBI

Trial Locations (3)

10126

University of Torino, Torino

98108

Veterans Administration Center-Seattle, Seattle

98109

Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium, Seattle

All Listed Sponsors

collaborator

National Cancer Institute (NCI)

NIH

lead

Fred Hutchinson Cancer Center

OTHER