Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

April 30, 2003

Primary Completion Date

April 30, 2008

Conditions
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Inv(16)(p13;q22)Adult Acute Myeloid Leukemia With t(15;17)(q22;q12)Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)Adult Acute Myeloid Leukemia With t(8;21)(q22;q22)Atypical Chronic Myeloid Leukemia, BCR-ABL1 NegativeChildhood Myelodysplastic SyndromesChronic Myelogenous Leukemia, BCR-ABL1 PositiveDisseminated NeuroblastomaMalignant NeoplasmOvarian ChoriocarcinomaOvarian Embryonal CarcinomaOvarian Immature TeratomaOvarian Mature TeratomaOvarian Mixed Germ Cell TumorOvarian Monodermal and Highly Specialized TeratomaOvarian PolyembryomaOvarian Yolk Sac TumorPreviously Treated Myelodysplastic SyndromesRecurrent Adult Acute Lymphoblastic LeukemiaRecurrent Adult Acute Myeloid LeukemiaRecurrent Adult Burkitt LymphomaRecurrent Adult Diffuse Large Cell LymphomaRecurrent Adult Diffuse Mixed Cell LymphomaRecurrent Adult Hodgkin LymphomaRecurrent Adult Immunoblastic Large Cell LymphomaRecurrent Adult Lymphoblastic LymphomaRecurrent Grade 3 Follicular LymphomaRecurrent Malignant Testicular Germ Cell TumorRecurrent Mantle Cell LymphomaRecurrent NeuroblastomaRecurrent Ovarian Epithelial CancerRecurrent Ovarian Germ Cell TumorRefractory Chronic Lymphocytic LeukemiaRefractory Multiple MyelomaRelapsing Chronic Myelogenous LeukemiaStage I Multiple MyelomaStage II Multiple MyelomaStage II Ovarian Epithelial CancerStage III Malignant Testicular Germ Cell TumorStage III Multiple MyelomaStage III Ovarian Epithelial CancerStage IIIA Breast CancerStage IIIB Breast CancerStage IIIC Breast CancerStage IV Breast CancerStage IV Ovarian Epithelial CancerTesticular ChoriocarcinomaTesticular Choriocarcinoma and Embryonal CarcinomaTesticular Choriocarcinoma and SeminomaTesticular Choriocarcinoma and TeratomaTesticular Choriocarcinoma and Yolk Sac TumorTesticular Embryonal CarcinomaTesticular Embryonal Carcinoma and SeminomaTesticular Embryonal Carcinoma and TeratomaTesticular Embryonal Carcinoma and Teratoma With SeminomaTesticular Embryonal Carcinoma and Yolk Sac TumorTesticular Embryonal Carcinoma and Yolk Sac Tumor With SeminomaTesticular TeratomaTesticular Yolk Sac TumorTesticular Yolk Sac Tumor and TeratomaTesticular Yolk Sac Tumor and Teratoma With Seminoma
Interventions
DRUG

ipilimumab

Given IV

DRUG

therapeutic allogeneic lymphocytes

Given IV

Trial Locations (5)

30342

Blood and Marrow Transplant Group of Georgia, Atlanta

Northside Hospital, Atlanta

92037

Scripps Clinic - La Jolla, La Jolla

92093-0960

University of California San Diego, La Jolla

02115

Dana-Farber Harvard Cancer Center, Boston

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH

NCT00060372 - Ipilimumab After Allogeneic Stem Cell Transplant in Treating Patients With Persistent or Progressive Cancer | Biotech Hunter | Biotech Hunter