Brain Irradiation in Treating Patients With Limited-Stage Small Cell Lung Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

265

Participants

Timeline

Start Date

February 28, 2003

Primary Completion Date

May 31, 2009

Study Completion Date

November 30, 2013

Conditions
Lung Cancer
Interventions
RADIATION

Prophylactic cranial irradiation, 2.5 Gy fx

Prophylactic cranial irradiation, 2.5 Gy once daily, M-F, in 10 fractions (fx) for a total of 25 Gy

RADIATION

Prophylactic cranial irradiation, 2.0 Gy fx

Prophylactic cranial irradiation, 2.0 Gy once daily, M-F, in 18 fractions (fx) for a total of 36 Gy

RADIATION

Prophylactic cranial irradiation, 1.5 Gy fx

Prophylactic cranial irradiation, 1.5 Gy twice daily, M-F, in 24 fractions (fx) for a total dose of 36 Gy

Trial Locations (222)

12601

Hudson Valley Oncology Associates, Poughkeepsie

13210

SUNY Upstate Medical University Hospital, Syracuse

14620

Highland Hospital of Rochester, Rochester

14642

James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester

17405

York Cancer Center at Apple Hill Medical Center, York

18015

St. Luke's Cancer Network at St. Luke's Hospital, Bethlehem

18301

Dale and Frances Hughes Cancer Center at Pocono Medical Center, East Stroudsburg

19001

Rosenfeld Cancer Center at Abington Memorial Hospital, Abington

19140

Fox Chase Cancer Center CCOP Research Base, Philadelphia

19141

Albert Einstein Cancer Center, Philadelphia

19713

CCOP - Christiana Care Health Services, Newark

19958

Tunnell Cancer Center at Beebe Medical Center, Lewes

21201

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore

21921

Union Hospital Cancer Program at Union Hospital, Elkton MD

26003

Schiffler Cancer Center at Wheeling Hospital, Wheeling

27534

Wayne Memorial Hospital, Incorporated, Goldsboro

Wayne Radiation Oncology, Goldsboro

28501

Kinston Medical Specialists, Kinston

28677

Iredell Memorial Hospital, Statesville

29425

Hollings Cancer Center at Medical University of South Carolina, Charleston

29615

CCOP - Greenville, Greenville

30501

Northeast Georgia Medical Center, Gainesville

32401

Bay Medical, Panama City

33136

University of Miami Sylvester Comprehensive Cancer Center - Miami, Miami

33176

Baptist-South Miami Regional Cancer Program, Miami

35294

Lurleen Wallace Comprehensive Cancer at University of Alabama - Birmingham, Birmingham

39581

Regional Cancer Center at Singing River Hospital, Pascagoula

43537

St. Luke's Hospital, Maumee

43560

Flower Hospital Cancer Center, Sylvania

43606

Toledo Hospital, Toledo

43608

St. Vincent Mercy Medical Center, Toledo

43614

Medical University of Ohio Cancer Center, Toledo

43616

St. Charles Mercy Hospital, Oregon

43617

CCOP - Toledo Community Hospital, Toledo

43623

Toledo Clinic, Incorporated - Main Clinic, Toledo

44112

Huron Hospital Cancer Care Center, Cleveland

44119

Euclid Hospital, Cleveland

44122

South Pointe Hospital Cancer Care Center, Warrensville Heights

44124

Hillcrest Cancer Center at Hillcrest Hospital, Mayfield Heights

44195

Cleveland Clinic Taussig Cancer Center, Cleveland

44460

Cancer Research UK Medical Oncology Unit at Churchill Hospital & Weatherall Institute of Molecular Medicine - Oxford, Salem

44691

Cancer Treatment Center, Wooster

44870

Firelands Regional Medical Center, Sandusky

44883

Mercy Hospital of Tiffin, Tiffin

44903

MedCentral - Mansfield Hospital, Mansfield

45267

Charles M. Barrett Cancer Center at University Hospital, Cincinnati

45801

St. Rita's Medical Center, Lima

45804

Lima Memorial Hospital, Lima

46016

Saint John's Cancer Center at Saint John's Medical Center, Anderson

46202

Veterans Affairs Medical Center - Indianapolis, Indianapolis

46350

Center for Cancer Therapy at LaPorte Hospital and Health Services, La Porte

46360

Saint Anthony Memorial Health Centers, Michigan City

46601

Memorial Hospital of South Bend, South Bend

46805

Parkview Regional Cancer Center at Parkview Health, Fort Wayne

48105

Veterans Affairs Medical Center - Ann Arbor, Ann Arbor

48202

Josephine Ford Cancer Center at Henry Ford Hospital, Detroit

49001

Borgess Medical Center, Kalamazoo

49007

Bronson Methodist Hospital, Kalamazoo

49017

Battle Creek Health System Cancer Care Center, Battle Creek

49085

Lakeland Regional Cancer Care Center - St. Joseph, Saint Joseph

49221

Hickman Cancer Center at Bixby Medical Center, Adrian

49307

Mecosta County Medical Center, Big Rapids

49423

Holland Community Hospital, Holland

49442

Hackley Hospital, Muskegon

49503

Butterworth Hospital at Spectrum Health, Grand Rapids

CCOP - Grand Rapids, Grand Rapids

Lacks Cancer Center at Saint Mary's Health Care, Grand Rapids

49506

Metro Health Hospital, Grand Rapids

49684

Munson Medical Center, Traverse City

50010

McFarland Clinic, PC, Ames

53066

Regional Cancer Center at Oconomowoc Memorial Hospital, Oconomowoc

53188

Waukesha Memorial Hospital Regional Cancer Center, Waukesha

53226

Medical College of Wisconsin Cancer Center, Milwaukee

53295

Veterans Affairs Medical Center - Milwaukee, Milwaukee

53405

All Saints Cancer Center at Wheaton Franciscan Healthcare, Racine

54143

Bay Area Cancer Care Center at Bay Area Medical Center, Marinette

54303

Green Bay Oncology, Limited at St. Mary's Hospital, Green Bay

St. Mary's Hospital Medical Center - Green Bay, Green Bay

54601

Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse

56002

Immanuel St. Joseph's, Mankato

56303

CentraCare Clinic - River Campus, Saint Cloud

57701

Rapid City Regional Hospital, Rapid City

60005

Northwest Community Hospital, Arlington Heights

60153

Cardinal Bernardin Cancer Center at Loyola University Medical Center, Maywood

60435

Joliet Oncology-Hematology Associates, Limited - West, Joliet

60507

Rush-Copley Cancer Care Center, Aurora

60525

La Grange Memorial Hospital, La Grange

61350

Community Hospital of Ottawa, Ottawa

61354

Illinois Valley Community Hospital, Peru

61356

Perry Memorial Hospital, Princeton

61362

St. Margaret's Hospital, Spring Valley

Valley Cancer Center, Spring Valley

61401

Galesburg Clinic, PC, Galesburg

Galesburg Cottage Hospital, Galesburg

InterCommunity Cancer Center of Western Illinois, Galesburg

61443

Kewanee Hospital, Kewanee

61455

McDonough District Hospital, Macomb

61520

Graham Hospital, Canton

61530

Eureka Community Hospital, Eureka

61554

Cancer Treatment Center at Pekin Hospital, Pekin

61614

Proctor Hospital, Peoria

61615

CCOP - Illinois Oncology Research Association, Peoria

Oncology Hematology Associates of Central Illinois, PC - Peoria, Peoria

61636

Methodist Medical Center of Illinois, Peoria

61637

OSF St. Francis Medical Center, Peoria

61701

St. Joseph Medical Center, Bloomington

61747

Hopedale Medical Complex, Hopedale

61761

BroMenn Regional Medical Center, Normal

Community Cancer Center, Normal

61801

Carle Cancer Center at Carle Foundation Hospital, Urbana

CCOP - Carle Cancer Center, Urbana

62321

Memorial Hospital, Carthage

62401

St. Anthony's Memorial Hospital, Effingham

62644

Mason District Hospital, Havana

63141

CCOP - St. Louis-Cape Girardeau, St Louis

63703

Cancer Institute of Cape Girardeau, LLC, Cape Girardeau

66606

Cotton-O'Neil Cancer Center, Topeka

St. Francis Comprehensive Cancer Center, Topeka

66720

Cancer Center of Kansas, PA - Chanute, Chanute

67042

Cancer Center of Kansas, PA - El Dorado, El Dorado

Cancer Center of Kansas, PA - Salina, Salina

67068

Cancer Center of Kansas, PA - Kingman, Kingman

67114

Cancer Center of Kansas, PA - Newton, Newton

67124

Cancer Center of Kansas, PA - Pratt, Pratt

67152

Cancer Center of Kansas, PA - Wellington, Wellington

67156

Cancer Center of Kansas, PA - Winfield, Winfield

67203

Associates in Womens Health, PA - North Review, Wichita

67208

Cancer Center of Kansas, PA - Medical Arts Tower, Wichita

67214

Cancer Center of Kansas, PA - Wichita, Wichita

CCOP - Wichita, Wichita

Via Christi Cancer Center at Via Christi Regional Medical Center, Wichita

Wesley Medical Center, Wichita

67357

Cancer Center of Kansas, PA - Parsons, Parsons

67801

Cancer Center of Kansas, PA - Dodge City, Dodge City

67901

Southwest Medical Center, Liberal

72764

Highlands Oncology Group - Springdale, Springdale

75390

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas

80909

Memorial Hospital Cancer Center - Colorado Springs, Colorado Springs

81502

St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center, Grand Junction

84106

Utah Cancer Specialists at UCS Cancer Center, Salt Lake City

84107

Cottonwood Hospital Medical Center, Murray

84143

LDS Hospital, Salt Lake City

84157

Jon and Karen Huntsman Cancer Center at Intermountain Medical Center, Murray

84403

Val and Ann Browning Cancer Center at McKay-Dee Hospital Center, Ogden

84604

Utah Valley Regional Medical Center - Provo, Provo

84770

Dixie Regional Medical Center - East Campus, St. George

85013

Arizona Oncology Services Foundation, Phoenix

85251

Virginia G. Piper Cancer Center at Scottsdale Healthcare - Osborn, Scottsdale

85260

Virginia G. Piper Cancer Center at Scottsdale Healthcare - Shea, Scottsdale

89102

University Medical Center of Southern Nevada, Las Vegas

89106

CCOP - Nevada Cancer Research Foundation, Las Vegas

89509

Radiation Oncology Associates - Reno, Reno

91767

Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical Center, Pomona

94609

CCOP - Bay Area Tumor Institute, Oakland

95603

Auburn Radiation Oncology, Auburn

95661

Radiation Oncology Center - Roseville, Roseville

95682

Radiation Oncology Centers - Cameron Park, Cameron Park

95687

Solano Radiation Oncology Center, Vacaville

95815

Radiological Associates of Sacramento Medical Group, Incorporated, Sacramento

95819

Mercy General Hospital, Sacramento

97030

Legacy Mount Hood Medical Center, Gresham

97062

Legacy Meridian Park Hospital, Tualatin

97210

Legacy Good Samaritan Hospital & Comprehensive Cancer Center, Portland

97222

Providence Milwaukie Hospital, Milwaukie

97225

CCOP - Columbia River Oncology Program, Portland

Providence St. Vincent Medical Center, Portland

97227

Legacy Emanuel Hospital and Health Center and Children's Hospital, Portland

97504

Dubs Cancer Center at Rogue Valley Medical Center, Medford

Providence Cancer Center at PMCC, Medford

97527

Three Rivers Community Hospital, Grants Pass

98104

Fred Hutchinson Cancer Research Center, Seattle

Harborview Medical Center, Seattle

98112

Group Health Central Hospital, Seattle

98225

St. Joseph Cancer Center, Bellingham

98310

Harrison Medical Center, Bremerton

98431

Madigan Army Medical Center - Tacoma, Tacoma

98668

Southwest Washington Medical Center Cancer Center, Vancouver

99202

Cancer Care Northwest - Spokane South, Spokane

92093-0658

Rebecca and John Moores UCSD Cancer Center, La Jolla

32610-0232

University of Florida Shands Cancer Center, Gainesville

46202-5289

Indiana University Melvin and Bren Simon Cancer Center, Indianapolis

47303-3499

Cancer Center at Ball Memorial Hospital, Muncie

52242-1002

Holden Comprehensive Cancer Center at University of Iowa, Iowa City

40536-0093

Lucille P. Markey Cancer Center at University of Kentucky, Lexington

02118

Boston University Cancer Research Center, Boston

02721

Hudner Oncology Center at Saint Anne's Hospital - Fall River, Fall River

02169

South Suburban Oncology Center, Quincy

48109-0942

University of Michigan Comprehensive Cancer Center, Ann Arbor

48201-1379

Barbara Ann Karmanos Cancer Institute, Detroit

49007-3731

West Michigan Cancer Center, Kalamazoo

08724

Ocean Medical Center at Meridian Health, Brick

08818

John F. Kennedy Medical Center, Edison

07740-6395

Monmouth Medical Center, Long Branch

08053

Fox Chase Virtua Health Cancer Program at Virtua Memorial Hospital Marlton, Marlton

07701

Booker Cancer Center at Riverview Medical Center, Red Bank

07871

Frederick R. and Betty M. Smith Cancer Treatment Center, Sparta

08755

J. Phillip Citta Regional Cancer Center at Community Medical Center, Toms River

08360

Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare, Vineland

08043

Cancer Institute of New Jersey at Cooper - Voorhees, Voorhees Township

14263-0001

Roswell Park Cancer Institute, Buffalo

10940-4199

Tucker Center for Cancer Care at Orange Regional Medical Center, Middletown

28233-3549

Presbyterian Cancer Center at Presbyterian Hospital, Charlotte

27835-6028

Leo W. Jenkins Cancer Center at ECU Medical School, Greenville

44309-2090

Summa Center for Cancer Care at Akron City Hospital, Akron

44710-1799

Aultman Cancer Center at Aultman Hospital, Canton

97213-2967

Providence Cancer Center at Providence Portland Medical Center, Portland

17033-0850

Penn State Cancer Institute at Milton S. Hershey Medical Center, Hershey

19107-5541

Kimmel Cancer Center at Thomas Jefferson University - Philadelphia, Philadelphia

19111-2497

Fox Chase Cancer Center - Philadelphia, Philadelphia

19612-6052

McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center, Reading

76012-2510

Arlington Cancer Center - Arlington, Arlington

77030-4009

M. D. Anderson Cancer Center at University of Texas, Houston

98122-4307

Swedish Cancer Institute at Swedish Medical Center - First Hill Campus, Seattle

98195-6043

University Cancer Center at University of Washington Medical Center, Seattle

98801-2028

Wenatchee Valley Medical Center, Wenatchee

54301-3526

Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center, Green Bay

54307-3508

St. Vincent Hospital Regional Cancer Center, Green Bay

R3E 0V9

CancerCare Manitoba, Winnipeg

M5G 2M9

Princess Margaret Hospital, Toronto

H2L 4M1

Hopital Notre-Dame du CHUM, Montreal

G1R 2J6

Centre Hospitalier Universitaire de Quebec, Québec

H2W 1S6

McGill Cancer Centre at McGill University, Montreal

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Radiation Therapy Oncology Group

NETWORK

NCT00057746 - Brain Irradiation in Treating Patients With Limited-Stage Small Cell Lung Cancer | Biotech Hunter | Biotech Hunter