6
Participants
Start Date
February 28, 2003
Primary Completion Date
October 31, 2009
Study Completion Date
October 31, 2009
CAMPATH-1H
Day-8 through Day-6 according to institutional SOPs
Anti-CD45
Day-5 400 μg/kg
Ara-C
day-7 through day-5 3000 mg/m2 q 12h
Cyclophosphamide
Day-7 through Day-6 45 mg/kg
Mesna
Days -7 and -6 45 mg/kg divided into 5 doses
Total Body Irradiation
150 cGy x 2 (5/6 matched related) 180 cGy x 2 (5/6 matched unrelated)
Texas Children's Hospital, Houston
The Methodist Hospital, Houston
The Methodist Hospital Research Institute
OTHER
Center for Cell and Gene Therapy, Baylor College of Medicine
OTHER
Baylor College of Medicine
OTHER