255
Participants
Start Date
April 30, 2002
Primary Completion Date
October 31, 2008
Study Completion Date
October 31, 2008
Bilateral Deep Brain Stimulation
The DBS site (STN or GPi) will be assigned on a random basis at the time the patient enters the surgical phase of the trial.
best medical therapy
"Participants will initially be randomized to DBS or to 6 months of best medical therapy. BMT participants will then proceed into the surgical phase of the trial. Effective 08/05/05, randomization to the BMT arm has been discontinued since the study has sufficient information to compare the outcomes of DBS and BMT patients at 6 months."
VA Medical Center, Philadelphia, Philadelphia
Pennsylvania Hospital, Philadelphia
Hunter Holmes McGuire VA Medical Center, Richmond
Medical College of Virginia, Richmond
Baylor College of Medicine, Houston
Michael E. DeBakey VA Medical Center (152), Houston
VA Greater Los Angeles Healthcare System, West LA, West Los Angeles
University of California at Los Angeles, Los Angeles
VA Medical Center, San Francisco, San Francisco
University of California at San Francisco, San Francisco
VA Medical Center, Portland, Portland
Oregon Health Sciences University, Portland
VA Puget Sound Health Care System, Seattle, Seattle
VA Medical Center, Iowa City, Iowa City
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
US Department of Veterans Affairs
FED