334
Participants
Start Date
December 31, 2002
Primary Completion Date
September 30, 2007
Study Completion Date
January 31, 2010
Interferon beta-1a
Interferon beta-1a 44 microgram (mcg) subcutaneously 3-times weekly for 36 months.
Alemtuzumab 12 mg
Alemtuzumab 12 milligram per day (mg/day) was given by intravenous infusion on 5 consecutive days during the first month and on 3 consecutive days at months 12 and 24 (the latter at the treating physicians' discretion if the cluster of differentiation 4+ \[CD4+\] T-cell count was \>=100\*10\^6 cells per liter).
Alemtuzumab 24 mg
Alemtuzumab 24 mg/day was given by intravenous infusion on 5 consecutive days during the first month and on 3 consecutive days at months 12 and 24 (the latter at the treating physicians' discretion if the CD4+ T-cell count was \>=100\*10\^6 cells per liter).
University Hospital an Medical Center, Stony Brook
University of Maryland -Maryland Center for MS, Baltimore
ALL-Trials Clinical Research, LLC, Winston-Salem
Medical Research and Health Education, Columbus
Neurological Service of Orlando, Orlando
Neurological Associates/ Research Dept., Pompano Beach
Axiom Clinical Research of Florida, Tampa
Neurology, PC, Knoxville
Associate in Neurology, Lexington
Fort Wayne Neurological Center, Fort Wayne
Wayne State University Department of Neurology, Detroit
Michigan Institute for Neurological Disorders, Farmington Hills
Michigan Medical P.C. Neurology, Grand Rapids
Mayo Clinic Rochester Department of Neurology, Rochester
Consultants in Neurology, Ltd, Northbrook
Clinical Trials, Inc, Little Rock
Neurological Associates of Tulsa, Inc, Tulsa
Dallas Neurological Associate, Richardson
Integra Clinical Research, LLC, San Antonio
Neurology Center of San Antonio, San Antonio
Central Texas Neurology Consultants PA, Round Rock
Neurologic Research Institute/Mile High Research Center, Denver
Mayo Clinic Scottsdale Arizona, Scottsdale
Nevada Neurological Consultants, Ltd., Las Vegas
Neuro-Therapeutics, Inc., Pasadena
Nerve Pro Research, Irvine
East Bay Physicians Medical Group, Berkeley
Russian State Medical University, Moscow
Neurology Scientific Center RAMS, Moscow
Institute of Human brain RAS, Saint Petersburg
Neurological Research Institute of the East Bay, Walnut Creek
Neurology Clinical Research, Inc., Sunrise
Neurosciencies and Pain Research, Allentown
Baylor College of Medicine, Houston
"Department of Neurology, University Hospital Osijek", Osijek
"Department of Neurology, Clinical Hospital Centre Rijeka", Rijeka
"Department of Neurology, Clinical Hospital Centre Zagreb", Zagreb
"Department of Neurology, General Hospital Sveti Duh", Zagreb
"Department of Neurology, University Hopsital Sestre Milosrdnice", Zagreb
Centrum Neurologii Klinicznej, Krakow
Samodzielny Publiczny Zakład Opieki Zdrowotnej, Lodz
Klinika Neurologii, Lublin
Oddzial Kliniczny Neurologii, Poznan
Instytut Psychiatrii i Neurologii, Warsaw
Katedra i Klinika Neurologii, Warsaw
Moscow City Hospital #11, Moscow
Moscow City Hospital #61, Moscow
St. Petersburg State Pavlov Medical University, Saint Petersburg
Addenbrooke's Hospital, Cambridge
Collaborators (1)
Bayer
INDUSTRY
Genzyme, a Sanofi Company
INDUSTRY