PEG-Interferon Alfa-2b in Treating Patients With Stage IV Melanoma

PHASE2CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

January 13, 2004

Primary Completion Date

August 31, 2012

Study Completion Date

June 30, 2014

Conditions
Melanoma (Skin)
Interventions
BIOLOGICAL

PEG-interferon alfa-2b

Patients receive PEG-interferon alfa-2b subcutaneously (SC) once weekly. Treatment continues until basic fibroblast growth factor level is suppressed to normal or until a maximum weekly dose is reached. If there is disease progression, patients then discontinue treatment. If there is no disease progression, patients receive PEG-interferon alfa-2b SC weekly for up to 1 year in the absence of disease progression or unacceptable toxicity.

Trial Locations (32)

15232

UPMC Cancer Centers, Pittsburgh

25304

West Virginia University Health Sciences Center - Charleston, Charleston

33805

Lakeland Regional Cancer Center at Lakeland Regional Medical Center, Lakeland

35294

UAB Comprehensive Cancer Center, Birmingham

44109

MetroHealth Cancer Care Center at MetroHealth Medical Center, Cleveland

49001

Borgess Medical Center, Kalamazoo

49007

Bronson Methodist Hospital, Kalamazoo

54601

Gundersen Lutheran Center for Cancer and Blood, La Crosse

60521

Hinsdale Hematology Oncology Associates, Hinsdale

61350

Community Hospital of Ottawa, Ottawa

61354

Illinois Valley Community Hospital, Peru

61356

Perry Memorial Hospital, Princeton

61401

Galesburg Clinic, PC, Galesburg

61455

McDonough District Hospital, Macomb

61520

Graham Hospital, Canton

61530

Eureka Community Hospital, Eureka

61554

Cancer Treatment Center at Pekin Hospital, Pekin

61614

Proctor Hospital, Peoria

61615

CCOP - Illinois Oncology Research Association, Peoria

Oncology Hematology Associates of Central Illinois, PC - Peoria, Peoria

61636

Methodist Medical Center of Illinois, Peoria

61637

OSF St. Francis Medical Center, Peoria

61701

St. Joseph Medical Center, Bloomington

61761

BroMenn Regional Medical Center, Normal

Community Cancer Center, Normal

62321

Memorial Hospital, Carthage

62526

Decatur Memorial Hospital Cancer Care Institute, Decatur

62644

Mason District Hospital, Havana

61104-2315

Swedish-American Regional Cancer Center, Rockford

49007-3731

West Michigan Cancer Center, Kalamazoo

44309-2090

Summa Center for Cancer Care at Akron City Hospital, Akron

44710-1799

Aultman Cancer Center at Aultman Hospital, Canton

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Eastern Cooperative Oncology Group

NETWORK

NCT00049530 - PEG-Interferon Alfa-2b in Treating Patients With Stage IV Melanoma | Biotech Hunter | Biotech Hunter