Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma

PHASE2CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

March 31, 1998

Primary Completion Date

October 31, 2005

Study Completion Date

February 29, 2008

Conditions
Lymphoma
Interventions
BIOLOGICAL

filgrastim

filgrastim (G-CSF) subcutaneously on days 5-21 and 28-42. Treatment repeats every 6 weeks for 2 courses in the absence of disease progression or unacceptable toxicity.

DRUG

cyclophosphamide

Oral cyclophosphamide on days 22-26. Treatment repeats every 6 weeks for 2 courses in the absence of disease progression or unacceptable toxicity.

DRUG

etoposide

Oral etoposide on days 1-3. Treatment repeats every 6 weeks for 2 courses in the absence of disease progression or unacceptable toxicity.

DRUG

lomustine

Oral lomustine on day 1 (course 1 only). Treatment repeats every 6 weeks for 2 courses in the absence of disease progression or unacceptable toxicity.

DRUG

procarbazine hydrochloride

Oral procarbazine on days 22-26. Treatment repeats every 6 weeks for 2 courses in the absence of disease progression or unacceptable toxicity.

Trial Locations (4)

10032

Herbert Irving Comprehensive Cancer Center at Columbia University, New York

44106-5065

Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center, Cleveland

Unknown

University of Nairobi College of Health Sciences, Nairobi

Uganda Cancer Institute, Kampala

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Case Comprehensive Cancer Center

OTHER

NCT00049439 - Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin's Lymphoma | Biotech Hunter | Biotech Hunter