Tipifarnib, Doxorubicin, and Cyclophosphamide in Treating Women With Locally Advanced Breast Cancer

PHASE2CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

February 28, 2003

Primary Completion Date

January 31, 2007

Conditions

Inflammatory Breast CancerStage II Breast CancerStage IIIA Breast CancerStage IIIB Breast CancerStage IIIC Breast Cancer

Interventions

DRUG

doxorubicin hydrochloride

DRUG

cyclophosphamide

Given IV

DRUG

tipifarnib

Given orally

BIOLOGICAL

filgrastim

Given subcutaneously

PROCEDURE

therapeutic conventional surgery

Undergo complete resection

OTHER

laboratory biomarker analysis

Correlative studies

Trial Locations (1)

Albert Einstein College of Medicine, The Bronx

All Listed Sponsors

lead

National Cancer Institute (NCI)

NIH

NCT00049114 - Tipifarnib, Doxorubicin, and Cyclophosphamide in Treating Women With Locally Advanced Breast Cancer | Biotech Hunter | Biotech Hunter