Combination Chemotherapy and Rituximab in Treating Patients With HIV-Associated Stage I, Stage II, Stage III, or Stage IV Non-Hodgkin's Lymphoma

PHASE2CompletedINTERVENTIONAL
Enrollment

106

Participants

Timeline

Start Date

March 31, 2003

Primary Completion Date

May 31, 2009

Study Completion Date

May 31, 2009

Conditions
AIDS-related Diffuse Large Cell LymphomaAIDS-related Immunoblastic Large Cell LymphomaAIDS-related Peripheral/Systemic LymphomaAIDS-related Small Noncleaved Cell Lymphoma
Interventions
BIOLOGICAL

rituximab

Given IV

DRUG

etoposide

Given IV

DRUG

doxorubicin hydrochloride

Given IV

DRUG

vincristine sulfate

Given IV

DRUG

prednisone

Given orally

DRUG

cyclophosphamide

Given IV

OTHER

laboratory biomarker analysis

Correlative studies

Trial Locations (1)

20850

AIDS - Associated Malignancies Clinical Trials Consortium, Rockville

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH

NCT00049036 - Combination Chemotherapy and Rituximab in Treating Patients With HIV-Associated Stage I, Stage II, Stage III, or Stage IV Non-Hodgkin's Lymphoma | Biotech Hunter | Biotech Hunter