Study of Combined RHUMAB VEGF and Capecitabine-based Chemoradiation for Patients With Locally Advanced Pancreatic Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

September 30, 2002

Primary Completion Date

July 31, 2006

Study Completion Date

July 31, 2006

Conditions
Pancreatic Cancer
Interventions
DRUG

Bevacizumab

Beginning 2 weeks prior to radiotherapy, dose of 5 mg/kg by vein then of 2.5 mg/kg during radiotherapy for four weeks every 2 weeks (three doses).

DRUG

Capecitabine

650mg/m\^2 taken by mouth twice a day 15-52 during the radiotherapy.

RADIATION

Radiotherapy

Radiography given once a day for 5 days at 50.4 Gy in 28 fractions over 5.5 weeks.

Trial Locations (1)

77030

University of Texas MDAnderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER