Study of Lonafarnib and Gleevec in Chronic Myelogenous Leukemia

PHASE1CompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

November 1, 2002

Primary Completion Date

April 10, 2006

Study Completion Date

April 10, 2006

Conditions
Chronic Myelogenous Leukemia
Interventions
DRUG

Lonafarnib (SCH66336)

"Participants in CHRONIC PHASE receive Gleevec 400 mg by mouth every day, and SCH66336 100 mg by mouth twice a day.~Participants in ACCELERATED OR BLASTIC PHASE receive SCH66336 100 mg by mouth twice a day.~Participants in ACCELERATED OR BLASTIC PHASE receive SCH66336 100 mg by mouth twice a day."

DRUG

Imatinib Mesylate (Gleevec)

"Participants in CHRONIC PHASE receive Gleevec 400 mg by mouth every day.~Participants in ACCELERATED OR BLASTIC PHASE receive Gleevec 600 mg by mouth every day."

Trial Locations (1)

77030

M.D. Anderson Cancer Center, Houston

All Listed Sponsors
lead

M.D. Anderson Cancer Center

OTHER

NCT00047502 - Study of Lonafarnib and Gleevec in Chronic Myelogenous Leukemia | Biotech Hunter | Biotech Hunter