Optimizing Electroconvulsive Therapy for Depression

PHASE4CompletedINTERVENTIONAL
Enrollment

340

Participants

Timeline

Start Date

February 28, 2001

Primary Completion Date

December 31, 2006

Study Completion Date

December 31, 2006

Conditions
DepressionDepressive DisorderBipolar Disorder
Interventions
PROCEDURE

High dosage electroconvulsive therapy

Participants will receive high dosage right unilateral ECT at six times the seizure threshold.

DRUG

Nortriptyline

Participants will receive nortriptyline.

DRUG

Venlafaxine

Participants will receive venlafaxine.

DRUG

Lithium

Participants will receive lithium.

PROCEDURE

Low dosage electroconvulsive therapy

Participants will receive low dosage bilateral ECT at one and a half times the seizure threshold.

Trial Locations (4)

10032

New York State Psychiatric Institute at Columbia University, New York

15213

Western Psychiatric Institute and Clinic, Pittsburgh

27103

Wake Forest University, Winston-Salem

63110

Washington University, St Louis

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

New York State Psychiatric Institute

OTHER

NCT00045916 - Optimizing Electroconvulsive Therapy for Depression | Biotech Hunter | Biotech Hunter