Efficacy and Safety of PG-530742 in the Treatment of Mild to Moderate Knee Osteoarthritis

PHASE2CompletedINTERVENTIONAL
Enrollment

395

Participants

Timeline

Start Date

July 31, 2002

Primary Completion Date

February 29, 2004

Study Completion Date

February 29, 2004

Conditions
Osteoarthritis, Knee
Interventions
DRUG

PG-530742

One 25 mg PG-530742 tablet, twice daily for for one year

DRUG

Placebo

One placebo tablet, twice daily for for one year

DRUG

50 mg PG-530742

One 50 mg PG-530742 tablet, twice daily for for one year

DRUG

100 mg PG-530742

100 mg PG-530742 tablet, twice a day for one year

DRUG

200 mg PG-530742

200 mg PG-530742 tablet, twice a day for one year

Trial Locations (23)

1027

National Institute of Rheumatology and Physiotherapy, Dept. of Rheumatology and Immunology, Frankel Leo u. 38-40, Budapest

National Institute of Rheumatology and Physiotherapy, Dept. of Rheumatology I and Metabolic Osteology, Frankel Leo u. 38-40, Budapest

National Institute of Rheumatology and Physiotherapy, Dept. of Rheumatology IV., Frankel Leo u. 38-40, Budapest

1113

Orthopedic Clinic, Karolina ut 17, Budapest

2026

Rehabilitation Hospital, Gizella telep, Visegrád

3529

Szent Ferenc Hospital, Department of Rheumatology, Csabai Kapu 42., Miskolc

9025

Petz A. Country Hospital, Department of Rheumatology, Hid utca 2., Győr

TW15 3EA

95 Stanwell Road, Ashford

HA 7 4LP

Royal National Orthapaedic Hsopital, Brackley Hill, Stanmore

Unknown

St Thomas Hospital, Lambeth Place Road, London

KT15 2BH

The Crouch Oak Practice, 45 Station Road, Addlestone, Addlestone

KT24 6QT

The Medical Centre, Kingston Avenue, East Horsley

CV37 6HE

Bridge House Medical Centre, Scholars Lane, Stratford-upon-Avon

RH10 7DX

Pound Hill Surgery, 1 Crawley Lane, Pound Hill, Crawley

B29 6JD

Dept of Rheumatology Selly Oak Hospital, Raddleburn Road, Selly Oak, Birmingham

B15 2SQ

Synexus Birmingham Clinical Research Centre, Birmingham Research Park, Edgbaston

TN 1 2DX

Grosvenor Medical Centre Clinical Trials Unit, 18 upper Grosvenor Road, Tunbridge Wells, Kent

E11 1NR

Dept of Rheumatology Whipps Cross University Hospital, Whipps Cross Road, London

SE22 8PT

Dept of Rheumatology Dulwich Hospital, East Dulwich, London

SE1 9RT

Rheumatology Department, Fourth Floor, Thomas Guy House, St Guy's House, London Bridge

RG2 7AG

Synexus Reading Clinical Research Centre, Whiteley Glebe, 11 Glebe Road, off Christchurch Gardens, Reading

TN10 3ET

Hildenborough Medical Group, Trenchwood Surgery, 264 Shipbourne Road, Tonbridge

WN6 9EW

Synexus Wrightington, Wrightington Hospital, Hall Lane, Awpley Bridge, Wigan

All Listed Sponsors
lead

Procter and Gamble

INDUSTRY

NCT00041756 - Efficacy and Safety of PG-530742 in the Treatment of Mild to Moderate Knee Osteoarthritis | Biotech Hunter | Biotech Hunter