Vaccine Therapy in Treating Patients With Stage IV or Recurrent Malignant Melanoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

28

Participants

Timeline

Start Date

March 31, 2002

Primary Completion Date

September 30, 2005

Study Completion Date

June 30, 2009

Conditions
Melanoma (Skin)
Interventions
BIOLOGICAL

dendritic cell-MART-1 peptide vaccine

Subjects will receive MART-1 adenovirus-transduced dendritic cells (DC)at dose of 10\^6 (for arm A) or 10\^7 (for arms B-E). Subjects will receive a total of three biweekly vaccinations given intradermally. If significant clinical or immunological response (to be defined later) is noted, subjects will be eligible for up to 6 additional monthly vaccine administrations.

Trial Locations (1)

90095-1781

Jonsson Comprehensive Cancer Center at UCLA, Los Angeles

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

lead

Jonsson Comprehensive Cancer Center

OTHER

NCT00039325 - Vaccine Therapy in Treating Patients With Stage IV or Recurrent Malignant Melanoma | Biotech Hunter | Biotech Hunter