Megadose CD34 Selected Progenitor Cells for Transplantation in Patients With Advanced Hematological Malignant Diseases

PHASE2CompletedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

September 30, 2001

Primary Completion Date

June 30, 2009

Study Completion Date

June 30, 2009

Conditions
LeukemiaLymphoma
Interventions
PROCEDURE

Megadose of CD34 Selected Progenitor Cells

Haploidentical peripheral blood progenitor cell (PBPC) transplants on Day 0.

DRUG

Melphalan

140 mg/m\^2 on day -8

DRUG

Thiotepa

10 mg/kg on day -7

DRUG

Fludarabine

160 mg/m\^2 over 4 days on days -6, -5, -4, -3

DRUG

Rabbit ATG

1.5 mg/kg of Rabbit ATG a day times 4 over 4 days on days -6, -5, -4, -3.

Trial Locations (1)

77030

MD Anderson Cancer Center, Houston

All Listed Sponsors
lead

M.D. Anderson Cancer Center

OTHER

NCT00038857 - Megadose CD34 Selected Progenitor Cells for Transplantation in Patients With Advanced Hematological Malignant Diseases | Biotech Hunter | Biotech Hunter