Study of Paclitaxel, Estramustine Phosphate and Thalidomide for Patients With Metastatic Androgen-Independent Prostate Carcinoma

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

October 31, 2000

Primary Completion Date

February 29, 2004

Study Completion Date

December 31, 2004

Conditions
Prostate Cancer
Interventions
DRUG

Estramustine

140 mg by mouth (po) three times a day on Days 1-5, 8-12

DRUG

Thalidomide

200 mg by mouth every day once a week with dose escalation every week if no dose limiting toxicity.

DRUG

Paclitaxel (Taxol)

100 mg/m\^2 by vein (IV) over 3 hours Day 3 and Day 10

Trial Locations (1)

77030

UT MD Anderson Cancer Center, Houston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Celgene

INDUSTRY

lead

M.D. Anderson Cancer Center

OTHER