Insulin-like Growth Factor-1 in Amyotrophic Lateral Sclerosis (ALS) Trial

PHASE3CompletedINTERVENTIONAL
Enrollment

330

Participants

Timeline

Start Date

June 30, 2003

Primary Completion Date

August 31, 2007

Study Completion Date

December 31, 2007

Conditions
Amyotrophic Lateral Sclerosis
Interventions
DRUG

Insulin like growth factor, type 1

0.05 mg per kg body weight given subcutaneously twice daily

DRUG

Placebo

The placebo represented the inert suspension vehicle for the IGF-1. It was given as equal volume as the active drug based upon body weight, subcutaneously twice daily.

Trial Locations (20)

10003

Beth Israel Medical Center, New York

14642

University of Rochester Medical Center, Rochester

19107

University of Pennsylvania, Pennsylvania Hospital, Philadelphia

26506

West Virginia University, Morgantown

30322

Emory University, Atlanta

32224

Mayo Clinic in Jacksonville, Jacksonville

39216

University of Mississippi, Jackson

43210

Ohio State University, Columbus

44195

Cleveland Clinic, Cleveland

45219

University of Cincinnati, Cincinnati

46202

Indiana University, Indianapolis

48109

University of Michigan Medical Center, Ann Arbor

48202

Henry Ford Hospital, Detroit

53226

Froedtert and Medical College Clinics, Milwaukee

55404

Hennepin County Medical Center, Minneapolis

55905

Mayo Clinic, Rochester

77030

Methodist Hospital, Houston

85259

Mayo Clinic in Scottsdale, Scottsdale

94115

California Pacific Medical Center, San Francisco

00935

University of Puerto Rico, San Juan

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

collaborator

ALS Association

OTHER

collaborator

Cephalon

INDUSTRY

lead

Mayo Clinic

OTHER

NCT00035815 - Insulin-like Growth Factor-1 in Amyotrophic Lateral Sclerosis (ALS) Trial | Biotech Hunter | Biotech Hunter