Radiation Therapy in Treating Patients With Stage II Prostate Cancer

PHASE3CompletedINTERVENTIONAL
Enrollment

1,534

Participants

Timeline

Start Date

March 31, 2002

Primary Completion Date

April 30, 2014

Study Completion Date

December 22, 2022

Conditions
Prostate Cancer
Interventions
RADIATION

70.2 Gy 3D-CRT/IMRT

Radiation will be delivered via 3D conformal radiation therapy (3D-CRT) or intensity modulated radiation therapy (IMRT) in 1.8 Gy minimum dose fractions to a total of 70.2 Gy in 39 Fractions. All fields treated once daily, five fractions per week. No more than 2% of the planning target volume and none of the clinical target volume may receive less than 70.2 Gy.

RADIATION

79.2 Gy 3D-CRT/IMRT

Radiation will be delivered via 3D conformal radiation therapy (3D-CRT) or intensity modulated radiation therapy (IMRT) in 1.8 Gy minimum dose fractions to a total of 79.2 Gy in 44 fractions. All fields treated once daily, five fractions per week. No more than 2% of the planning target volume and none of the clinical target volume may receive less than 79.2 Gy.

Trial Locations (86)

11209

Veterans Affairs Medical Center - Brooklyn, Brooklyn

11215

New York Methodist Hospital, Brooklyn

13210

SUNY Upstate Medical University Hospital, Syracuse

16803

Mount Nittany Medical Center, State College

19010

Bryn Mawr Hospital, Bryn Mawr

19096

CCOP - Main Line Health, Wynnewood

Lankenau Cancer Center at Lankenau Hospital, Wynnewood

19115

MNAP Oncologic Center, Philadelphia

19141

Albert Einstein Cancer Center, Philadelphia

20010

Washington Cancer Institute at Washington Hospital Center, Washington D.C.

21044

Central Maryland Oncology Center, Columbia

21201

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore

24541

Danville Regional Medical Center, Danville

27607

Cancer Centers of North Carolina - Raleigh, Raleigh

Rex Cancer Center at Rex Hospital, Raleigh

32401

Bay Medical, Panama City

37916

Thompson Cancer Survival Center, Knoxville

39581

Regional Cancer Center at Singing River Hospital, Pascagoula

44691

Cancer Treatment Center, Wooster

45069

Precision Radiotherapy at University Pointe, West Chester

45267

Charles M. Barrett Cancer Center at University Hospital, Cincinnati

46320

Oncology Center at Saint Margaret Mercy Healthcare Center, Hammond

48073

William Beaumont Hospital - Royal Oak Campus, Royal Oak

48105

Veterans Affairs Medical Center - Ann Arbor, Ann Arbor

48910

Breslin Cancer Center at Ingham Regional Medical Center, Lansing

49201

Foote Memorial Hospital, Jackson

53051

Community Memorial Hospital Cancer Care Center, Menomonee Falls

53226

Medical College of Wisconsin Cancer Center, Milwaukee

53405

All Saints Cancer Center at Wheaton Franciscan Healthcare, Racine

54601

Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse

56303

CentraCare Clinic - River Campus, Saint Cloud

61636

Methodist Medical Center of Illinois, Peoria

63110

Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis, St Louis

64050

Independence Regional Health Center, Independence

64108

Truman Medical Center - Hospital Hill, Kansas City

64111

Saint Luke's Cancer Institute at Saint Luke's Hospital, Kansas City

64114

Kansas City Cancer Center at St. Joseph's Medical Mall, Kansas City

St. Joseph Medical Center, Kansas City

64116

North Kansas City Hospital, Kansas City

Parvin Radiation Oncology, Kansas City

64131

CCOP - Kansas City, Kansas City

64154

Radiation Oncology Associates of Kansas City at Northland Radiation Oncology Center, Kansas City

64506

Heartland Regional Medical Center, Saint Joseph

66044

Lawrence Memorial Hospital, Lawrence

66112

Providence Medical Center, Kansas City

66204

Shawnee Mission Medical Center, Shawnee Mission

66209

Menorah Medical Center, Overland Park

66210

Johnson County Radiation Therapy, Overland Park

75390

Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas, Dallas

78236

Wilford Hall Medical Center, Lackland Air Force Base

84143

LDS Hospital, Salt Lake City

84157

Jon and Karen Huntsman Cancer Center at Intermountain Medical Center, Murray

84403

Val and Ann Browning Cancer Center at McKay-Dee Hospital Center, Ogden

84770

Dixie Regional Medical Center - East Campus, St. George

87102

Lovelace Medical Center - Downtown, Albuquerque

89503

Saint Mary's Regional Medical Center, Reno

90822

Veterans Affairs Medical Center - Long Beach, Long Beach

94115

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco

95815

Radiological Associates of Sacramento Medical Group, Incorporated, Sacramento

47303-3499

Cancer Center at Ball Memorial Hospital, Muncie

40536-0093

Lucille P. Markey Cancer Center at University of Kentucky, Lexington

48109-0942

University of Michigan Comprehensive Cancer Center, Ann Arbor

49007-3731

West Michigan Cancer Center, Kalamazoo

08103

Cancer Institute of New Jersey at Cooper University Hospital - Camden, Camden

08043

Cancer Institute of New Jersey at Cooper - Voorhees, Voorhees Township

14263-0001

Roswell Park Cancer Institute, Buffalo

44309-2090

Summa Center for Cancer Care at Akron City Hospital, Akron

19301-1792

Cancer Center of Paoli Memorial Hospital, Paoli

19107-5541

Kimmel Cancer Center at Thomas Jefferson University - Philadelphia, Philadelphia

19612-6052

McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center, Reading

78234-6200

Brooke Army Medical Center, Fort Sam Houston

23708-2197

Naval Medical Center - Portsmouth, Portsmouth

T2N 4N2

Tom Baker Cancer Centre - Calgary, Calgary

T6G 1Z2

Cross Cancer Institute at University of Alberta, Edmonton

R3E 0V9

CancerCare Manitoba, Winnipeg

E2L 4L2

Saint John Regional Hospital, Saint John

A1B 3V6

Doctor H. Bliss Murphy Cancer Centre, St. John's

P3E 5J1

Northeastern Ontario Regional Cancer Centre, Greater Sudbury

L8V 5C2

Margaret and Charles Juravinski Cancer Centre, Hamilton

N6A 4L6

London Regional Cancer Program at London Health Sciences Centre, London

P7B 6V4

Cancer Care Program at Thunder Bay Regional Health Sciences, Thunder Bay

M4N 3M5

Edmond Odette Cancer Centre at Sunnybrook, Toronto

H2L 4M1

Hopital Notre-Dame du CHUM, Montreal

H2W 1S6

McGill Cancer Centre at McGill University, Montreal

G1R 2J6

Centre Hospitalier Universitaire de Quebec, Québec

S7N 4H4

Saskatoon Cancer Centre at the University of Saskatchewan, Saskatoon

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Radiation Therapy Oncology Group

NETWORK

NCT00033631 - Radiation Therapy in Treating Patients With Stage II Prostate Cancer | Biotech Hunter | Biotech Hunter