Long Term Treatment of Herpes Simplex Encephalitis (HSE) With Valacyclovir

PHASE3CompletedINTERVENTIONAL
Enrollment

91

Participants

Timeline

Start Date

September 30, 2000

Primary Completion Date

June 30, 2010

Study Completion Date

February 28, 2011

Conditions
Encephalitis
Interventions
DRUG

Valacyclovir

Valacyclovir is a L-valyl ester of acyclovir. Valacyclovir is provided in 500 mg tablets, 4 tablets (500 mg tablets) 3 times a day (every 8 hours) for 90 days.

DRUG

Placebo

Placebo (identical to active drug in appearance) 500 mg tablets, 4 tablets 3 times daily for 90 days.

Trial Locations (21)

21287

Johns Hopkins University, Baltimore

22908

University of Virginia Health System, Charlottesville

43614

University of Toledo, Toledo

55905

Mayo Clinic, Rochester

60611

Northwestern University Feinberg School of Medicine, Chicago

66160

University of Kansas Medical Center, Kansas City

70112

Tulane University Health Sciences Center, New Orleans

80220

University of Colorado, Denver

85013

St. Joseph's Hospital and Medical Center - Barrow Neurological Institute - Phoenix, Phoenix

87131

University of New Mexico, Albuquerque

95817

University of California Davis Medical Center, Sacramento

35294-2050

University of Alabama at Birmingham, Birmingham

63110-0250

Saint Louis University Hospital - School of Medicine - Department of Neurology & Psychiatry, St Louis

R3E 0W3

University of Manitoba - Medical Microbiology and Infectious Diseases, Winnipeg

K7L 2V7

Kingston General Hospital - Internal Medicine - Neurology, Kingston

Unknown

University of Gothenburg - Sahlgrenska Academy, Gothenberg

niversity of Lund - Infectious Disease, Lund

Karolinska University Hospital, Huddinge, Stockholm

Umea University - Infectious Diseases, Umeå

Uppsala University Hospital, Uppsala

NW3 2PF

University College London - Royal Free Campus - Virology, London

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00031486 - Long Term Treatment of Herpes Simplex Encephalitis (HSE) With Valacyclovir | Biotech Hunter | Biotech Hunter