NCT00025363View on ClinicalTrials.gov

Comparison of Chemotherapy Regimens in Treating Children With Relapsed or Progressive Rhabdomyosarcoma

PHASE2CompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

November 30, 2001

Primary Completion Date

October 31, 2007

Conditions
Alveolar Childhood RhabdomyosarcomaEmbryonal Childhood RhabdomyosarcomaEmbryonal-botryoid Childhood RhabdomyosarcomaPreviously Treated Childhood RhabdomyosarcomaRecurrent Childhood Rhabdomyosarcoma
Interventions
DRUG

vincristine sulfate

Given IV

DRUG

irinotecan hydrochloride

Given IV

DRUG

cyclophosphamide

Given IV

DRUG

doxorubicin hydrochloride

Given IV

DRUG

ifosfamide

Given IV

DRUG

etoposide

Given IV

DRUG

tirapazamine

Given IV

BIOLOGICAL

filgrastim

Given SC

BIOLOGICAL

sargramostim

Given SC

OTHER

pharmacological study

Correlative studies

OTHER

pharmacogenomic studies

Correlative studies

OTHER

laboratory biomarker analysis

Correlative studies

Trial Locations (1)

91006-3776

Children's Oncology Group, Arcadia

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH

NCT00025363 - Comparison of Chemotherapy Regimens in Treating Children With Relapsed or Progressive Rhabdomyosarcoma | Biotech Hunter | Biotech Hunter