Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors

PHASE2CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

January 31, 2000

Study Completion Date

April 30, 2011

Conditions
Brain and Central Nervous System Tumors
Interventions
BIOLOGICAL

filgrastim

DRUG

carboplatin

DRUG

cyclophosphamide

DRUG

thiotepa

PROCEDURE

conventional surgery

PROCEDURE

peripheral blood stem cell transplantation

RADIATION

radiation therapy

Trial Locations (21)

12

Our Lady's Hospital for Sick Children Crumlin, Dublin

B4 6NH

Birmingham Children's Hospital, Birmingham

BS2 8BJ

Bristol Royal Hospital for Children, Bristol

CB2 2QQ

Addenbrooke's Hospital at Cambridge University Hospitals NHS Foundation Trust, Cambridge

LS9 7TF

Leeds Cancer Centre at St. James's University Hospital, Leeds

LE1 5WW

Leicester Royal Infirmary, Leicester

L12 2AP

Royal Liverpool Children's Hospital, Alder Hey, Liverpool

EC1A 7BE

Saint Bartholomew's Hospital, London

WC1N 3JH

Great Ormond Street Hospital for Children NHS Trust, London

WIT 3AA

University College of London Hospitals, London

M27 4HA

Central Manchester and Manchester Children's University Hospitals NHS Trust, Manchester

NE7 7DN

Newcastle Upon Tyne Hospitals NHS Trust, Newcastle upon Tyne

NG7 2UH

Queen's Medical Centre, Nottingham

0X3 9DU

Oxford Radcliffe Hospital, Oxford

S10 2TH

Children's Hospital - Sheffield, Sheffield

SO16 6YD

Southampton University Hospital NHS Trust, Southampton

SM2 5PT

Royal Marsden NHS Foundation Trust - Surrey, Sutton

BT12 6BE

Royal Belfast Hospital for Sick Children, Belfast

AB25 2ZN

Aberdeen Royal Infirmary, Aberdeen

EH9 1LF

Royal Hospital for Sick Children, Edinburgh

G3 8SJ

Royal Hospital for Sick Children, Glasgow

All Listed Sponsors
lead

Children's Cancer and Leukaemia Group

OTHER

NCT00025077 - Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patients With Recurrent Medulloblastoma or Primitive Neuroectodermal and Pineal Tumors | Biotech Hunter | Biotech Hunter