NCT00023998View on ClinicalTrials.gov

Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

PHASE2CompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

July 31, 2001

Primary Completion Date

November 30, 2005

Study Completion Date

May 31, 2007

Conditions
Metastatic Osteosarcoma
Interventions
DRUG

doxorubicin hydrochloride

Given IV

DRUG

cisplatin

Given IV

DRUG

methotrexate

Given IV

DRUG

leucovorin calcium

Given IV or orally

BIOLOGICAL

filgrastim

Given IV

PROCEDURE

therapeutic conventional surgery

Undergo resection

RADIATION

radiation therapy

Undergo radiotherapy

DRUG

etoposide

Given IV

DRUG

ifosfamide

Given IV

BIOLOGICAL

trastuzumab

Given IV

OTHER

laboratory biomarker analysis

Correlative studies

Trial Locations (1)

91006-3776

Children's Oncology Group, Arcadia

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH

NCT00023998 - Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma | Biotech Hunter | Biotech Hunter