Comparison of Surgical and Medical Treatment for Congestive Heart Failure and Coronary Artery Disease

PHASE3CompletedINTERVENTIONAL
Enrollment

2,136

Participants

Timeline

Start Date

January 31, 2002

Primary Completion Date

November 30, 2015

Study Completion Date

November 30, 2015

Conditions
Cardiovascular DiseasesCoronary DiseaseHeart Failure, CongestiveHeart Diseases
Interventions
PROCEDURE

CABG surgery plus MED

CABG plus standard medication management for Coronary Artery Disease

DRUG

Active Medication Alone

Standard medication for coronary artery disease and heart failure management.

PROCEDURE

CABG plus MED and SVR

H02: the experimental arm receives active medical therapy and CABG and surgical ventricular restoration whereas the control group receives active medical therapy and CABG; for H01: the experimental arm receives active medical therapy and CABG whereas the control group receives active medical therapy alone

Trial Locations (1)

27715

Duke University Medical Center, Durham

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Duke University

OTHER