NCT00022737 - Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia | Biotech Hunter

Enrollment

220

Participants

Timeline

Start Date

October 31, 2002

Primary Completion Date

October 31, 2006

Conditions

Childhood Acute Lymphoblastic Leukemia in RemissionRecurrent Childhood Acute Lymphoblastic Leukemia

Interventions

BIOLOGICAL

filgrastim

Given SC

DRUG

asparaginase

Given IM

DRUG

cyclophosphamide

Given IV

DRUG

cyclosporine

Given IV

DRUG

cytarabine

Given IT and IV

DRUG

daunorubicin hydrochloride

Given IV

DRUG

dexamethasone

Given orally

DRUG

etoposide

Given IV

DRUG

ifosfamide

Given IV

DRUG

imatinib mesylate

Given orally

DRUG

leucovorin calcium

Given IV or orally

DRUG

mercaptopurine tablet

Given orally

DRUG

methotrexate

Given IT, IV, and orally

DRUG

pegaspargase

Given IM

DRUG

vincristine sulfate

Given IV

PROCEDURE

allogeneic bone marrow transplantation

Undergo allogeneic bone marrow, peripheral blood stem cell, or umbilical cord blood transplantation

PROCEDURE

peripheral blood stem cell transplantation

Undergo allogeneic bone marrow, peripheral blood stem cell, or umbilical cord blood transplantation

PROCEDURE

umbilical cord blood transplantation

Undergo allogeneic bone marrow, peripheral blood stem cell, or umbilical cord blood transplantation

RADIATION

radiation therapy

Undergo radiation therapy

Trial Locations (1)

91006-3776

Children's Oncology Group, Arcadia

All Listed Sponsors

lead

National Cancer Institute (NCI)

NIH