5,145
Participants
Start Date
June 30, 2001
Primary Completion Date
September 30, 2012
Study Completion Date
June 30, 2020
Lifestyle Intervention
The lifestyle intervention is implemented with individual supervision and group sessions and is aimed at achieving and maintaining at least a 7% decrease in weight from baseline and 175 minutes per week in physical activity. It is implemented during a four-year period with the most intensive application during the first year, less frequent attention during the next three years, and a minimum of twice yearly contacts during an extended follow-up period. To help participants achieve and maintain weight loss, a variety of diet strategies (e.g. prepared meals and liquid formula), exercise strategies, and optional weight loss medications are utilized based on a preset algorithm and participant progress.
Diabetes Support and Education
Participants assigned to diabetes support and education are offered three sessions each year in diabetes management and social support.
Columbia University, New York
University of Pittsburgh, Pittsburgh
University of Pennsylvania Medical Center, Philadelphia
Johns Hopkins Pro-Health, Baltimore
The University of Alabama at Birmingham, Birmingham
The University of Tennessee, Memphis, Memphis
Louisiana State University, Baton Rouge
Baylor College of Medicine, Houston
University of Texas Health Sciences Center, San Antonio
Southwestern American Indian Center, Phoenix
Northern Navajo Medical Center, Shiprock
University of Southern California, Los Angeles
University of Washington, Seattle
University of Colorado Health Sciences Center, Aurora
Diabetes Center, Boston
Joslin Diabetes Center, Boston
University of Minnesota, Minneapolis
The Miriam Hospital, Providence
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
National Heart, Lung, and Blood Institute (NHLBI)
NIH
National Institute of Nursing Research (NINR)
NIH
National Institute on Minority Health and Health Disparities (NIMHD)
NIH
Office of Research on Women's Health (ORWH)
NIH
Centers for Disease Control and Prevention
FED
Wake Forest University Health Sciences
OTHER