Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Neuroblastoma

PHASE2CompletedINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

April 30, 2001

Primary Completion Date

September 30, 2005

Study Completion Date

January 31, 2012

Conditions
Neuroblastoma
Interventions
BIOLOGICAL

filgrastim

BIOLOGICAL

sargramostim

DRUG

carboplatin

DRUG

cisplatin

DRUG

cyclophosphamide

DRUG

doxorubicin hydrochloride

DRUG

etoposide

DRUG

etoposide phosphate

DRUG

ifosfamide

DRUG

isotretinoin

DRUG

melphalan

DRUG

thiotepa

DRUG

vincristine sulfate

PROCEDURE

conventional surgery

PROCEDURE

peripheral blood stem cell transplantation

RADIATION

radiation therapy

Trial Locations (9)

6001

Princess Margaret Hospital for Children, Perth

19104

Children's Hospital of Philadelphia, Philadelphia

30342

AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Scottish RiteCampus, Atlanta

54449

CCOP - Marshfield Clinic Research Foundation, Marshfield

76508

CCOP - Scott and White Hospital, Temple

77030

Baylor College of Medicine, Houston

97225

CCOP - Columbia River Oncology Program, Portland

02111

Floating Hospital for Children, Boston

02115

Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK

NCT00017368 - Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Neuroblastoma | Biotech Hunter | Biotech Hunter