Chemotherapy, Hormone Therapy, and Radiation Therapy in Treating Patients With Locally Advanced Prostate Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

May 31, 2001

Primary Completion Date

July 31, 2007

Study Completion Date

May 31, 2008

Conditions
Prostate Cancer
Interventions
DRUG

carboplatin

AUC=6 week one of each 4 week cycle

DRUG

estramustine

2 tablets tid PO 5 of 7 days per week each 4 week cycle

DRUG

paclitaxel

80 mg/sq m IV infusion over 1 hour weekly for ea 4 week cycle

RADIATION

radiation therapy

77.4 Gy in 1.8 Gy fractions

DRUG

leuprolide or goserelin acetate

7.5 mg IM injection once every 4 weeks for 6 months

Trial Locations (23)

10021

Memorial Sloan-Kettering Cancer Center, New York

13057

CCOP - Hematology-Oncology Associates of Central New York, Syracuse

13126

Oswego Hospital, Oswego

13210

SUNY Upstate Medical University Hospital, Syracuse

Veterans Affairs Medical Center - Syracuse, Syracuse

13215

Community General Hospital of Greater Syracuse, Syracuse

20007

Lombardi Comprehensive Cancer Center at Georgetown University Medical Center, Washington D.C.

21201

Greenebaum Cancer Center at University of Maryland Medical Center, Baltimore

Veterans Affairs Medical Center - Baltimore, Baltimore

24541

Danville Regional Medical Center, Danville

27534

Wayne Memorial Hospital, Incorporated, Goldsboro

Wayne Radiation Oncology, Goldsboro

28501

Lenoir Memorial Cancer Center, Kinston

29401

Roper St. Francis Cancer Center at Roper Hospital, Charleston

29601

Bon Secours St. Francis Health System, Greenville

29615

CCOP - Greenville, Greenville

63017

Saint Luke's Hospital, Chesterfield

89102

University Medical Center of Southern Nevada, Las Vegas

89106

CCOP - Nevada Cancer Research Foundation, Las Vegas

20307-5001

Walter Reed Army Medical Center, Washington D.C.

01655

UMASS Memorial Cancer Center - University Campus, Worcester

27893-3428

Wilson Medical Center, Wilson

43210-1240

Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University, Columbus

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Alliance for Clinical Trials in Oncology

OTHER

NCT00016913 - Chemotherapy, Hormone Therapy, and Radiation Therapy in Treating Patients With Locally Advanced Prostate Cancer | Biotech Hunter | Biotech Hunter