Phase I Pilot Study of Total-Body Irradiation, Anti-Thymocyte Globulin and Cyclophosphamide Followed By Syngeneic or Autologous Peripheral Blood Stem Cell Transplantation in Patients With Multiple Sclerosis

PHASE1CompletedINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

December 31, 1997

Conditions
Multiple Sclerosis
Interventions
DRUG

anti-thymocyte globulin

DRUG

cyclophosphamide

DRUG

filgrastim

DRUG

prednisone

PROCEDURE

peripheral blood stem cell transplantation

PROCEDURE

irradiation

Trial Locations (6)

27710

Duke University Medical Center, Durham

63110

Washington University Barnard Cancer Center, St Louis

80262

University of Colorado Cancer Center, Denver

91010

City of Hope National Medical Center, Duarte

98109

Fred Hutchinson Cancer Research Center, Seattle

68198-3330

University of Nebraska Medical Center, Omaha

All Listed Sponsors
lead

Fred Hutchinson Cancer Center

OTHER

NCT00014755 - Phase I Pilot Study of Total-Body Irradiation, Anti-Thymocyte Globulin and Cyclophosphamide Followed By Syngeneic or Autologous Peripheral Blood Stem Cell Transplantation in Patients With Multiple Sclerosis | Biotech Hunter | Biotech Hunter