NCT00010335View on ClinicalTrials.gov

Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders

PHASE1CompletedINTERVENTIONAL
Enrollment

6

Participants

Timeline

Start Date

November 30, 2000

Primary Completion Date

July 31, 2010

Study Completion Date

May 31, 2011

Conditions
Systemic SclerosisSystemic Lupus ErythematosusDermatomyositisJuvenile Rheumatoid ArthritisAutoimmune Diseases
Interventions
PROCEDURE

Stem Cell Transplantation

Participants will receive a stem cell transplantation along with irradiation and the drugs anti-thymocyte globulin, cyclophosphamide, and filgrastim as noted in the text of this record.

DEVICE

CD34 selection

CD34+ cells are separated from the rest of the peripheral blood stem cells.

Trial Locations (1)

98109

Fred Hutchinson Cancer Research Center, Seattle

All Listed Sponsors
lead

Fred Hutchinson Cancer Center

OTHER

NCT00010335 - Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders | Biotech Hunter | Biotech Hunter