NCT00009646View on ClinicalTrials.gov

Trial of Indomethacin Prophylaxis in Preterm Infants (TIPP)

PHASE3CompletedINTERVENTIONAL
Enrollment

1,202

Participants

Timeline

Start Date

November 30, 1993

Primary Completion Date

March 31, 1999

Study Completion Date

March 31, 2001

Conditions
Infant, Very Low Birth WeightInfant, PrematureDuctus Arteriosus, Patent
Interventions
DRUG

indomethacin

Indocid P.D.A., Merck Frosst, Kirkland, Que., Canada, and Merck, West Point, Pa

DRUG

Indomethacin

0.1 mg per kilogram of body weight

DRUG

Placebo

0.1 mg per kilogram of body weight

Trial Locations (9)

30303

Emory University, Atlanta

33136

University of Miami, Miami

35233

University of Alabama at Birmingham, Birmingham

44106

Case Western Reserve University, Rainbow Babies and Children's Hospital, Cleveland

48201

Wayne State University, Detroit

75235

University of Texas Southwestern Medical Center at Dallas, Dallas

87131

University of New Mexico, Albuquerque

94304

Stanford University, Palo Alto

02905

Brown University, Women & Infants Hospital of Rhode Island, Providence

All Listed Sponsors
collaborator

Medical Research Council of Canada

OTHER

collaborator

National Center for Research Resources (NCRR)

NIH

lead

NICHD Neonatal Research Network

NETWORK