350
Participants
Start Date
April 30, 2000
Study Completion Date
March 31, 2004
Cyclosporine
Anti-human thymocyte globulin (rabbit)
Anti-human thymocyte globulin (rabbit) will be given at a dose of 1.5 mg/kg while undergoing transplantation. Second and subsequent doses of Thymoglobulin® will be administered if, at 24 hours post-anastomosis, the serum creatinine has not decreased by at least 20% from the pre-transplant level. Additional Anti-human thymocyte globulin (rabbit) will be given at a dose of 1.5mg/kg daily for a minimum of 5 days to a maximum of 7 days.
Tacrolimus
Ilene Blechman-Krom, Rockville
National Institute of Allergy and Infectious Diseases (NIAID)
NIH