Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer

PHASE2TerminatedINTERVENTIONAL
Enrollment

4

Participants

Timeline

Start Date

January 31, 2000

Primary Completion Date

November 15, 2001

Study Completion Date

September 10, 2002

Conditions
Esophageal Cancer
Interventions
DRUG

carboplatin

Carboplatin AUC 6 days 1 and 22

DRUG

fluorouracil

5FU 225mg/m2 continuous infusion on days 1-42 during radiation

DRUG

paclitaxel

taxol

PROCEDURE

conventional surgery

RADIATION

radiation therapy

The initial fields should be treated AP:PA when possible to a dose of 4500 cGy in 180 cGy fractions

Trial Locations (6)

20010

Washington Cancer Institute, Washington D.C.

Washington Hospital Center, Washington D.C.

21218

Union Memorial Hospital, Baltimore

21225

Harbor Hospital Center, Baltimore

21237

Franklin Square Hospital Center, Baltimore

21239

Good Samaritan Hospital of Maryland, Baltimore

All Listed Sponsors
lead

Medstar Health Research Institute

OTHER