27
Participants
Start Date
February 29, 2000
Primary Completion Date
October 31, 2006
Study Completion Date
December 31, 2011
etoposide
Etoposide IV 500 mg/m2/day over 24 hours Days -5, -4, -3
ifosfamide
Ifosfamide 3,333 mg/m2/day IV over 2 hours (total dose 10,000 mg/m2)Days -8, -7, -6
topotecan hydrochloride
Topotecan 21.3 mg/m2/day (total dose 64 mg/m2 ) IV over 30 minutes Days -8, -7, -6
autologous bone marrow transplantation
Mesna
Mesna 1,111 mg/m2/dose IV over 30 minutes; 30 minutes before and 4 and 8 hours after ifosfamide (total dose 10,000 mg/m2) Days -8, -7, -6
H. Lee Moffitt Cancer Center and Research Institute, Tampa
National Cancer Institute (NCI)
NIH
H. Lee Moffitt Cancer Center and Research Institute
OTHER