63
Participants
Start Date
September 30, 2000
Primary Completion Date
October 31, 2007
Study Completion Date
March 31, 2012
LHRH agonist
Lupron: 22.5mg IM injection q 12 wks x 2 OR Zoladex: 10.8 mg subQ injection q 12 wks x 2
antiandrogen
flutamide 250 mg PO tid for 4 wks OR casodex 50 mg PO daily for 4 wks
radiation therapy
4500 cGy total dose given days 1-5 for 5 weeks following initiation of androgen suppression (25 fractions)
Brachytherapy boost
Iodine 125 0.3 to 0.5 U per seed OR palladium 103 1.04 to 1.4 U per seed as implant; prescribed dose of I-125 100 Gy (TG-43) and Pd-103 90 Gy
CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C., Syracuse
SUNY Upstate Medical University Hospital, Syracuse
Veterans Affairs Medical Center - Syracuse, Syracuse
Community General Hospital of Greater Syracuse, Syracuse
Roswell Park Cancer Institute, Buffalo
CCOP - Christiana Care Health Services, Newark
St. Francis Hospital, Wilmington
Beebe Medical Center, Lewes
Union Hospital Cancer Center at Union Hospital, Elkton MD
Danville Regional Medical Center, Danville
Comprehensive Cancer Center at Wake Forest University, Winston-Salem
Wayne Memorial Hospital, Incorporated, Goldsboro
Presbyterian Cancer Center at Presbyterian Hospital, Charlotte
Zimmer Cancer Center at New Hanover Regional Medical Center, Wilmington
Florida Hospital Cancer Institute at Florida Hospital Orlando, Orlando
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University, Columbus
Missouri Baptist Cancer Center, St Louis
Arch Medical Services, Incoroporated at Center for Cancer Care Research, St Louis
CCOP - Kansas City, Kansas City
Ellis Fischel Cancer Center at University of Missouri - Columbia, Columbia
Washoe Cancer Services at Washoe Medical Center - Reno, Reno
Brigham and Women's Hospital, Boston
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute, Boston
Hudner Oncology Center at Saint Anne's Hospital, Fall River
UMASS Memorial Cancer Center - University Campus, Worcester
Cancer Institute of New Jersey at the Cooper University Hospital - Voorhees, Camden
National Cancer Institute (NCI)
NIH
Alliance for Clinical Trials in Oncology
OTHER