240
Participants
Start Date
February 29, 2000
Primary Completion Date
March 31, 2004
Study Completion Date
March 31, 2006
busulfan
arm 1: 0.44 mg/kg every 6 hours, IV over 2 hours, day -7 to -4
cyclophosphamide
arm 2: 60 mg/kg every 24 hrs for 2 doses, IV over 2 hrs, days -5 and -4
cyclosporine
both arms per published schedule
methotrexate
GVHD: 15 mg/m2 day 1, 10 mg/m2 day 3, 6 and 11 by IV
allogeneic bone marrow transplantation
day 0
radiation therapy
both arms: 1200 cGy total dose (6 x 200 fractions)
Herbert Irving Comprehensive Cancer Center, New York
Cleveland Clinic Taussig Cancer Center, Cleveland
Jewish Hospital of Cincinnati, Inc., Cincinnati
Miami Valley Hospital, Dayton
CCOP - Dayton, Kettering
Henry Ford Hospital, Detroit
Loyola University Medical Center, Maywood
St. John's Health System, Springfield
CCOP - Cancer Research for the Ozarks, Springfield
Cancer Center of Kansas - Wichita, Wichita
MBCCOP - LSU Health Sciences Center, New Orleans
Tulane University School of Medicine, New Orleans
Memorial Medical Center, New Orleans
University of Arkansas for Medical Sciences, Little Rock
University of Oklahoma Health Sciences Center, Oklahoma City
CCOP - Scott and White Hospital, Temple
Scott and White Clinic, Temple
Methodist Health Care System, San Antonio
Brooke Army Medical Center, Fort Sam Houston
Texas Tech University Health Science Center, Lubbock
Health Science Center, Lubbock
University of Colorado Cancer Center, Denver
Mountain States Tumor Institute, Boise
Huntsman Cancer Institute, Salt Lake City
LDS Hospital, Salt Lake City
Arizona Cancer Center, Tucson
Scripps Clinic, La Jolla
Chao Family Comprehensive Cancer Center, Orange
Northern California Cancer Specialists Medical Clinic, Walnut Creek
Alta Bates Comprehensive Cancer Center, Berkeley
Sutter Cancer Center, Sacramento
University of California Davis Cancer Center, Sacramento
Cancer Research Center of Hawaii, Honolulu
Queen's Medical Center, Honolulu
St. Francis Medical Center, Honolulu
Legacy Cancer Services, Portland
CCOP - Columbia River Program, Portland
Providence St. Vincent Medical Center, Portland
CCOP - Virginia Mason Research Center, Seattle
Swedish Cancer Institute, Seattle
Good Samaritan Medical Center, Phoenix
Cancer Center and Beckman Research Institute, City of Hope, Duarte
USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles
Jonsson Comprehensive Cancer Center, UCLA, Los Angeles
St. Joseph Hospital - Orange, Orange
Stanford University Medical Center, Stanford
University of Kansas Medical Center, Kansas City
CCOP - Wichita, Wichita
Albert B. Chandler Medical Center, University of Kentucky, Lexington
Lucille Parker Markey Cancer Center, University of Kentucky, Lexington
Louisiana State University School of Medicine, New Orleans
Louisiana State University Health Sciences Center - Shreveport, Shreveport
Boston Medical Center, Boston
Cancer Research Center, Boston
University of Michigan Comprehensive Cancer Center, Ann Arbor
Barbara Ann Karmanos Cancer Institute, Detroit
University of Mississippi Medical Center, Jackson
St. Louis University Health Sciences Center, St Louis
Oregon Cancer Center, Portland
Wilford Hall - 59th Medical Wing, Lackland Air Force Base
University of Texas Health Science Center at San Antonio, San Antonio
Fred Hutchinson Cancer Research Center, Seattle
University of Washington Medical Center, Seattle
Franciscan Health System, Tacoma
CCOP - Northwest, Tacoma
Princess Margaret Hospital, Toronto
National Cancer Institute (NCI)
NIH
SWOG Cancer Research Network
NETWORK