NCT00005092View on ClinicalTrials.gov

Chemotherapy, Radiation Therapy, and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

May 28, 1999

Primary Completion Date

August 28, 2002

Study Completion Date

August 28, 2002

Conditions
LeukemiaLymphomaMultiple Myeloma and Plasma Cell NeoplasmMyelodysplastic Syndromes
Interventions
DRUG

Cyclophosphamide

IV over 2 hours on days 2 and 3

DRUG

Psoralen

Psoralen treated T-cell allogeneic transplant on day 9

DRUG

Thiotepa

IV over 2 hours on day 1

PROCEDURE

Allogeneic bone marrow transplantation

Preserved stem cell or bone marrow allogeneic transplant plus psoralen treated T-cell allogeneic transplant on day 9

PROCEDURE

In vitro-treated peripheral blood stem cell transplantation (PBSCT)

Preserved stem cell or bone marrow allogeneic transplant plus psoralen treated T-cell allogeneic transplant on day 9

RADIATION

Radiation Therapy (RT)

Whole body radiotherapy on days 5-8.

Trial Locations (3)

60612

University of Illinois at Chicago, Chicago

63110

Washington University Barnard Cancer Center, St Louis

77030-4009

University of Texas - MD Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

M.D. Anderson Cancer Center

OTHER