2,502
Participants
Start Date
December 31, 2000
Primary Completion Date
February 28, 2011
Study Completion Date
December 31, 2016
Carotid Endarterectomy (CEA)
CEA involves a neck incision and physical removal of the plaque from the inside of the carotid artery.
Carotid Artery Stenting (CAS)
CAS involves insertion of a catheter or tube into an artery in the groin and then threading the catheter through the arteries of the body to the location of the plaque within the carotid artery in the neck. A stent is then placed to cover the plaque and hold the artery open. Participants randomized to this arm of the trial were treated using the RX Acculink Carotid Stent with or without the RX Accunet Embolic Protection Device.
NYU School of Medicine, New York
The Feinstein Institute for Medical Research, New York
Weill Medical College of Cornell University, New York
Columbia Presbyterian, New York
Richmond University Medical Center, Staten Island
Westchester Medical Center, Valhalla
St. Francis Hospital, Port Washington
Center for Vascular Awareness, Inc., Albany
Millard Fillmore SUNY Buffalo, Buffalo
University of Rochester, Rochester
Heritage Valley Medical Group, Beaver
Allegheny Singer Research Institute, Pittsburgh
UPMC Presbyterian Shadyside, Pittsburgh
Geisinger Medical Center, Danville
Lehigh Valley Hospital, Allentown
University of Pennsylvania, Philadelphia
Thomas Jefferson University Hospital, Philadelphia
Christiana Care Health Services, Inc., Newark
Adventist Healthcare, Inc., Takoma Park
Johns Hopkins University, Baltimore
Anne Arundel Health System Research Institute, Annapolis
University of Virginia, Charlottesville
Charleston Area Medical Center, Charleston
Forsyth Radiological Associates, Winston-Salem
Wake Forest University, Winston-Salem
UNC at Chapel Hill, Chapel Hill
Duke University Medical Center, Durham
The Charlotte-Mecklenburg Hospital Authority, Charlotte
South Carolina Heart Center, Columbia
Piedmont Hospital/Fuqua Heart Center, Atlanta
Emory University, Atlanta
St. Joseph's of Atlanta, Atlanta
St. Joseph's Candler Health System, Savannah
Mayo Clinic, Jacksonville
Florida Hospital Neuroscience Institute, a division of Adventist Health System/Sunbelt, Inc., Orlando
Orlando Regional Medical Center, Orlando
Miami Cardiac & Vascular Institute of Baptist Hospital of Miami, Inc., Miami
University of South Florida Board of Trustees, Tampa
Morton Plant Hospital, Clearwater
Leesburg Medical Center, Leesburg
The Board of Trustees of the University of Alabama for the University of Alabama at Birmingham, Birmingham
Metro Knoxville HMA, Knoxville
Baptist Memorial Hospital, Memphis
Mississippi Baptist Medical Center, Inc., Jackson
Baptist Healthcare System, Inc., Lexington
Midwest Ohio Health Research Institute, Columbus
The Toledo Hospital, Toledo
University of Toledo, Toledo
The Cleveland Clinic Lerner College Of Medicine of CWRU, Cleveland
Christ Hospital, Cincinnati
University of Cincinnati, Cincinnati
St. Vincent's Hospital, Indianapolis
Lutheran Medical Group, LLC,, Fort Wayne
Parkview Hospital, Inc., Fort Wayne
William Beaumont Hospital, Royal Oak
Providence St. John Hopital, Southfield
University of Michigan, Ann Arbor
Michigan Heart & Vascular Institute/St. Joseph's Mercy Hospital, Ypsilanti
Henry Ford Health System, Detroit
St. John Hospital and Medical Center, Detroit
Michigan Vascular Research Center, Flint
Spectrum Health Hospital, Grand Rapids
Catholic Health Initiatives /Mercy Hospital Center, Des Moines
St. Luke's Medical Center, Milwaukee
Marshfield Clinic, Marshfield
North Memorial Health Care, Robbinsdale
Mayo Clinic Rochester/St. Mary's, Rochester
St. Patrick's Hospital International Heart Institute of MT, Missoula
Alexian Brothers Specialty Group, Elk Grove Village
Loyola University of Chicago, Maywood
Central Dupage Hospital, Winfield
Norwestern Memorial Hospital, Chicago
Peoria Radiology Research and Education, Peoria
Prarie Cardiology-St. John's Hospital, Springfield
Southern Illinois School of Medicine, Springfield
Mercy Hospitals East Communities, St Louis
Heartland Physician Services, LLC, Kansas City
Ochsner Foundation Hospital, New Orleans
Vascular Surgery Associates, Baton Rouge
Board of Trustees of the University of Arkansas, Little Rock
Oklahoma Foundation for Cardiovascular Research, Oklahoma City
The University of Texas Southwestern Medical Center at Dallas, Dallas
Scott & White Memorial Hospital, Temple
Houston Methodist Hospital, Houston
UT Houston Memorial, Houston
Intermountain Health Services, Salt Lake City
Dignity Health dba St. Joseph's Hospital & Medical Center, Phoenix
Mayo Clinic Arizona, Scottsdale
The Arizona Board of Regents for the University of Arizona, Tucson
USC University Hospital & LA County Hospital, Los Angeles
The Regents of the University of California, Los Angeles
Kaiser Permanente Medical Center, San Diego
Northern California Institute for Research and Education, San Francisco
Catholic Healthcare West, Stockton
Oregon Health Science University, Portland
Rogue Valley Medical Center, Medford
Swedish Health Services, Seattle
Providence Health & Services - Washington, Spokane
Massachusetts General Hospital, Boston
Steward St. Elizabeth's Medical Center of Boston, Inc., Boston
Beth Israel Deaconess Medical Center, Boston
Brigham and Womens Hospital, Inc., Boston
Cape Cod Health Care, Inc.,, Hyannis
Dartmouth College and the constituent members of DARTMOUTH HITCHCOCK MEDICAL CENTER, Lebanon
St. Michael's Medical Center, Newark
Rhode Island Hospital, Providence
Governors of the University of Calgary and the Calgary Health Region, Calgary
The University of British Columbia and The Vancouver Coastal Health Authority, Vancouver
St. Boniface General Hospital, Winnipeg
The Credit Valley Hospital and Trillium Health Centre, Mississauga
Ottawa Hospital Research Institute, Ottawa
St. Michael's Hospital, Toronto
University Health Network, Toronto
Lawson Health Research Institute, Toronto
CHU de Québec, Québec
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
University of Alabama at Birmingham
OTHER
Rutgers, The State University of New Jersey
OTHER