NCT00004142View on ClinicalTrials.gov

Radiofrequency Ablation Followed By Hepatic Artery Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

August 5, 1998

Primary Completion Date

December 9, 2003

Study Completion Date

December 9, 2003

Conditions
Colorectal CancerMetastatic Cancer
Interventions
DRUG

Floxuridine

Part of hepatic arterial chemotherapy on days 1-7. Treatment repeats every 5 weeks for 6 courses.

DRUG

Fluorouracil (5-FU)

Part of hepatic arterial chemotherapy over 1 hour on days 15, 22, and 29. Treatment repeats every 5 weeks for 6 courses.

PROCEDURE

Conventional surgery

Open laparotomy to identify target tumor in liver using intraoperative ultrasound.

PROCEDURE

Radiofrequency ablation

Radiofrequency tissue ablation over 20 minutes to each tumor.

Trial Locations (1)

77030-4009

University of Texas - MD Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

M.D. Anderson Cancer Center

OTHER

NCT00004142 - Radiofrequency Ablation Followed By Hepatic Artery Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver | Biotech Hunter | Biotech Hunter