O6-benzylguanine And Carmustine in Treating Patients With Multiple Myeloma

PHASE2CompletedINTERVENTIONAL
Enrollment

17

Participants

Timeline

Start Date

September 30, 1999

Primary Completion Date

August 31, 2004

Study Completion Date

September 30, 2004

Conditions
Multiple Myeloma and Plasma Cell Neoplasm
Interventions
DRUG

O6-benzylguanine

Patients receive O6-benzylguanine IV over 60 minutes. Courses repeat every 6 weeks in the absence of disease progression or unacceptable toxicity. Patients receive 2 additional courses beyond attainment of best response.

DRUG

carmustine

Followed 1 hour later by carmustine IV over 60 minutes. Courses repeat every 6 weeks in the absence of disease progression or unacceptable toxicity. Patients receive 2 additional courses beyond attainment of best response.

Trial Locations (3)

44109

MetroHealth Medical Center, Cleveland

60637-1470

University of Chicago Cancer Research Center, Chicago

44106-5065

Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center, Cleveland

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Case Comprehensive Cancer Center

OTHER

NCT00004072 - O6-benzylguanine And Carmustine in Treating Patients With Multiple Myeloma | Biotech Hunter | Biotech Hunter