SWOG-9704 Chemoradiotherapy and Peripheral Stem Cell Transplantation Compared With Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma

PHASE3CompletedINTERVENTIONAL
Enrollment

397

Participants

Timeline

Start Date

July 31, 1997

Primary Completion Date

June 1, 2008

Study Completion Date

October 31, 2013

Conditions
Lymphoma
Interventions
BIOLOGICAL

rituximab

375 mg/m2 IV every 21 days

DRUG

CHOP regimen

DRUG

carmustine

DRUG

cyclophosphamide

DRUG

doxorubicin hydrochloride

DRUG

etoposide

DRUG

prednisone

DRUG

vincristine sulfate

PROCEDURE

bone marrow ablation with stem cell support

PROCEDURE

peripheral blood stem cell transplantation

RADIATION

radiation therapy

Trial Locations (15)

97201

Oregon Health & Science University, Portland

T2N 4N2

Tom Baker Cancer Centre - Calgary, Calgary

T6G 1Z2

Cross Cancer Institute at University of Alberta, Edmonton

R3E 0V9

CancerCare Manitoba, Winnipeg

E1C 6Z8

Moncton Hospital, Moncton

AIB 3V6

Doctor H. Bliss Murphy Cancer Centre, St. John's

B3H 1V7

Nova Scotia Cancer Centre, Halifax

L8V 5C2

Margaret and Charles Juravinski Cancer Centre, Hamilton

N6A 4L6

London Regional Cancer Program at London Health Sciences Centre, London

M4N 3M5

Odette Cancer Centre at Sunnybrook, Toronto

H2L 4M1

Hopital Notre-Dame du CHUM, Montreal

H4J 1C5

Hopital Du Sacre-Coeur de Montreal, Montreal

G1R 2J6

Centre Hospitalier Universitaire de Quebec, Québec

G1S 4L8

Hopital du Saint-Sacrement - Quebec, Québec

S7N 4H4

Saskatoon Cancer Centre at the University of Saskatchewan, Saskatoon

Sponsors
All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

Cancer and Leukemia Group B

NETWORK

collaborator

Eastern Cooperative Oncology Group

NETWORK

collaborator

NCIC Clinical Trials Group

NETWORK

lead

SWOG Cancer Research Network

NETWORK