NCT00003958 - Combination Chemotherapy in Treating Patients With Previously Untreated Rhabdomyosarcoma | Biotech Hunter

Enrollment

702

Participants

Timeline

Start Date

September 30, 2002

Primary Completion Date

October 31, 2007

Conditions

Adult Malignant MesenchymomaAdult RhabdomyosarcomaAlveolar Childhood RhabdomyosarcomaChildhood Malignant MesenchymomaEmbryonal Childhood RhabdomyosarcomaEmbryonal-botryoid Childhood RhabdomyosarcomaNonmetastatic Childhood Soft Tissue SarcomaPreviously Untreated Childhood RhabdomyosarcomaStage I Adult Soft Tissue SarcomaStage II Adult Soft Tissue SarcomaStage III Adult Soft Tissue Sarcoma

Interventions

BIOLOGICAL

dactinomycin

Given IV

DRUG

vincristine sulfate

Given IV

DRUG

cyclophosphamide

Given IV

PROCEDURE

therapeutic conventional surgery

Undergo surgery

RADIATION

radiation therapy

Undergo radiotherapy

DRUG

topotecan hydrochloride

Given IV

BIOLOGICAL

filgrastim

Given SC

BIOLOGICAL

sargramostim

Given SC

OTHER

laboratory biomarker analysis

Correlative studies

Trial Locations (1)

91006-3776

Children's Oncology Group, Arcadia

All Listed Sponsors

collaborator

National Cancer Institute (NCI)

NIH

lead

Children's Oncology Group

NETWORK