44
Participants
Start Date
January 31, 1998
Primary Completion Date
November 30, 2007
Study Completion Date
January 31, 2012
anti-thymocyte globulin
antithymocyte globulin IV for three days on days -3 to -1
busulfan
If TBI is not tolerated, busulfan is substituted and administered orally every 6 hours for 4 days on days -8 to -5.
cyclosporine
Cyclosporine begin on day -2 and continue for 6 months.
melphalan
melphalan IV for three days on days -4 to -2
methylprednisolone
Methylprednisolone IV for three days on days -3 to -1. Methylprednisolone begin on day -2 and continue for 6 months.
umbilical cord blood transplantation
On day 0, patients receive umbilical cord blood infusion.
radiation therapy
9 fractions of total body irradiation (TBI) on days -9 to -5
Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
National Cancer Institute (NCI)
NIH
Case Comprehensive Cancer Center
OTHER