39
Participants
Start Date
June 1, 1999
Primary Completion Date
February 28, 2010
Study Completion Date
May 31, 2011
cisplatin
Cisplatin was administered as part of the neoadjuvant regimen. It was given at a dose of 75 mg/m² via IV over approximately one hour, on day 1 of each cycle. Three cycles were given.
fluorouracil
Postoperative regimen 5-FU, along with Leucovorin, was given by IV bolus, with 5-FU given immediately after the Leucovorin
leucovorin calcium
Both 5-FU and Leucovorin will be given via IV bolus, with Leucovorin given immediately before 5-FU.
paclitaxel
Paclitaxel was administered as part of the neoadjuvant regimen. It was given at a dose of 175 mg/m² as a 3 hour continuous intravenous infusion on day 1. Three cycles were given.
surgery
"The surgical procedure performed involved a radical subtotal or total gastrectomy.~A complete surgical resection was required"
radiation therapy
Concomitant chemotherapy and radiation therapy course: 5-FU 400 mg/m²/day + Leucovorin 20 mg/m²/day on days 1-4 of week one and days 1-3 of week 5 of XRT. Combined chemotherapy and radiation therapy were to begin 4 weeks after day 1 of the initial course of chemotherapy
Albert Einstein Comprehensive Cancer Center, The Bronx
University of Rochester Cancer Center, Rochester
CCOP - MainLine Health, Wynnewood
Emory University Hospital - Atlanta, Atlanta
Veterans Affairs Medical Center - Tennessee Valley Healthcare System - Nashville Campus, Nashville
Veterans Affairs Medical Center - Indianapolis (Roudebush), Indianapolis
CCOP - Ann Arbor Regional, Ann Arbor
Medical College of Wisconsin, Milwaukee
Veterans Affairs Medical Center - Milwaukee (Zablocki), Milwaukee
CCOP - Marshfield Medical Research and Education Foundation, Marshfield
CCOP - Metro-Minnesota, Saint Louis Park
CCOP - Evanston, Evanston
Veterans Affairs Medical Center - Lakeside Chicago, Chicago
CCOP - Carle Cancer Center, Urbana
CCOP - Missouri Valley Cancer Consortium, Omaha
CCOP - Ochsner, New Orleans
CCOP - Colorado Cancer Research Program, Inc., Denver
Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago
Indiana University Cancer Center, Indianapolis
CCOP - Cedar Rapids Oncology Project, Cedar Rapids
New England Medical Center Hospital, Boston
CCOP - Kalamazoo, Kalamazoo
Morristown Memorial Hospital, Morristown
Cancer Institute of New Jersey, New Brunswick
Raritan Bay Medical Center, Perth Amboy
Somerset Medical Center, Somerville
Ireland Cancer Center, Cleveland
CCOP - Toledo Community Hospital Oncology Program, Toledo
University of Pennsylvania Cancer Center, Philadelphia
Vanderbilt-Ingram Cancer Center, Nashville
National Cancer Institute (NCI)
NIH
ECOG-ACRIN Cancer Research Group
NETWORK