Bone Marrow Transplantation in Treating Patients With Chronic Lymphocytic Leukemia

PHASE2CompletedINTERVENTIONAL
Enrollment

49

Participants

Timeline

Start Date

March 5, 1991

Primary Completion Date

June 5, 2002

Study Completion Date

June 5, 2002

Conditions
Leukemia
Interventions
DRUG

Cyclophosphamide

Daily intravenous infusions of cyclophosphamide for two days,

PROCEDURE

Allogeneic Bone Marrow Transplantation

After completion of the TBI, allogeneic or autologous bone marrow infused intravenously.

PROCEDURE

Autologous Bone Marrow Transplantation

After completion of the TBI, allogeneic or autologous bone marrow infused intravenously.

RADIATION

Total Body Irradiation (TBI)

Following 2 days of cyclophosphamide, TBI in four daily exposures then bone marrow transplant.

Trial Locations (1)

77030

University of Texas - MD Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

M.D. Anderson Cancer Center

OTHER