116
Participants
Start Date
October 30, 1995
Primary Completion Date
February 4, 2004
Study Completion Date
February 4, 2004
Bleomycin Sulfate (BLM)
Filgrastim (G-CSF)
Arm 1: Administered subcutaneously (SC) beginning on day 5 and continuing until blood counts recover through Course 1 then 2 courses administered before PBSC harvest and same regimen with Course 2, then daily with Day 0 of infusion.
Recombinant Interferon Alfa
Carmustine
Arm 1, Course 3, IV over 1 hour on day -6.
Cisplatin (CDDP)
Cyclophosphamide
Cytarabine (ARA-C)
Arm 1, Course 3, every 12 hours on days -5 to -2.
Etoposide (VP-16)
Course 1, IV over 2 hours every 12 hours on days 1-3; Course 3, every 12 hours on days -5 to -2.
Idarubicin
Ifosfamide
During Course 1, IV continuously; Course 2, IV continuously on days 1-3.
Leucovorin Calcium
Melphalan
Methotrexate
Methylprednisolone
mitoxantrone hydrochloride (DHAD)
Arm 1, Course 2, IV on day 1.
Vincristine Sulfate
Peripheral Blood Stem Cell Transplantation
Infusion of stem cells on Day 0.
Radiation Therapy
University of Texas - MD Anderson Cancer Center, Houston
National Cancer Institute (NCI)
NIH
M.D. Anderson Cancer Center
OTHER