Combination Chemotherapy in Treating Patients With Multiple Myeloma

PHASE3CompletedINTERVENTIONAL
Enrollment

595

Participants

Timeline

Start Date

June 2, 1995

Primary Completion Date

May 3, 2004

Study Completion Date

December 21, 2009

Conditions
Multiple Myeloma and Plasma Cell Neoplasm
Interventions
DRUG

dexamethasone

40 mg daily for four days given orally and repeated every 28 days should commence on day 29 of the twelfth cycle of induction therapy.

DRUG

melphalan

9 mg/m2 daily for 4 days given orally on an empty stomach every 4 weeks

DRUG

prednisone

100 mg daily for 4 days given orally on a full stomach with each cycle of melphalan

Trial Locations (37)

55805

St. Mary's/Duluth Clinic Health System, Duluth

T2N 4N2

Tom Baker Cancer Center - Calgary, Calgary

T6G 1Z2

Cross Cancer Institute, Edmonton

V1Y 5L3

British Columbia Cancer Agency - Centre for the Southern Interior, Kelowna

V5Z 4E6

British Columbia Cancer Agency, Vancouver

V6Z 1Y6

Providence Health Care - Vancouver, Vancouver

V8R 6V5

British Columbia Cancer Agency - Vancouver Island Cancer Centre, Victoria

E1C 6ZB

Moncton Hospital, Moncton

E1C 8X3

Doctor Leon Richard Oncology Centre, Moncton

E2L 4L2

Saint John Regional Hospital, Saint John

A1B 3V6

Newfoundland Cancer Treatment and Research Foundation, St. John's

B3H 2Y9

Nova Scotia Cancer Centre, Halifax

L6W 2Z8

William Osler Health Centre, Brampton

P3E 5J1

Northeastern Ontario Regional Cancer Centre, Sudbury, Greater Sudbury

L8V 5C2

Cancer Care Ontario-Hamilton Regional Cancer Centre, Hamilton

K7L 5P9

Kingston Regional Cancer Centre, Kingston

N6A 4L6

Cancer Care Ontario-London Regional Cancer Centre, London

L5B 1B8

Trillium Health Centre, Mississauga

L5M 2N1

Credit Valley Hospital, Mississauga

L3Y 2P9

Southlake Regional Health Centre, Newmarket

L1G 2B9

Lakeridge Health Oshawa, Oshawa

P6B 1Y5

Algoma District Medical Group, Sault Ste. Marie

L2R 5K3

Hotel Dieu Health Sciences Hospital - Niagara, St. Catharines

M4C 3E7

Toronto East General Hospital, Toronto

M4N 3M5

Toronto Sunnybrook Regional Cancer Centre, Toronto

M5B 1W8

St. Michael's Hospital - Toronto, Toronto

M5G 2C4

Toronto General Hospital, Toronto

M5G 2M9

Princess Margaret Hospital, Toronto

M9N 1N8

Humber River Regional Hospital, Weston

N8W 2X3

Cancer Care Ontario - Windsor Regional Cancer Centre, Windsor

C1A 8T5

Queen Elizabeth Hospital, PEI, Charlottetown

J1H 5N4

CHUS-Hopital Fleurimont, Fleurimont

J4V 2H1

Hopital Charles Lemoyne, Greenfield Park

H2W 1S6

McGill University, Montreal

G1J 1Z4

Hopital de L'Enfant Jesus, Québec

G1S 4L8

Hopital du Saint-Sacrement, Quebec, Québec

S4T 7T1

Allan Blair Cancer Centre, Regina

Sponsors
All Listed Sponsors
lead

NCIC Clinical Trials Group

NETWORK